C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TAP binding protein (tapasin)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000231925 TAPBP 9606 - 6:33299694-33314387 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000426633 TAPBP-008 33303573-33314212 protein_coding
  ENST00000434618 TAPBP-001 33299694-33314387 protein_coding
  ENST00000437116 TAPBP-003 33304268-33314041 retained_intron
  ENST00000456592 TAPBP-206 33304300-33314387 protein_coding
  ENST00000467025 TAPBP-010 33305109-33314215 protein_coding
  ENST00000475304 TAPBP-007 33301685-33314251 protein_coding
  ENST00000476333 TAPBP-004 33313014-33313955 retained_intron
  ENST00000480730 TAPBP-002 33303663-33314049 retained_intron
  ENST00000489157 TAPBP-006 33301760-33314254 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000426633ENST00000434618ENST00000437116
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000426633 N/A N/A N/A N/A 6.196±0.00 N/A N/A 4.806±0.00 N/A 1.639±0.00 N/A N/A N/A
ENST00000434618 61.396±0.00 71.937±0.00 12.250±5.29 30.614±0.00 7.278±0.42 19.694±0.00 17.212±9.43 14.529±12.54 14.657±10.10 21.472±0.00 18.121±10.83 44.334±14.49 9.482±7.50
ENST00000437116 N/A N/A N/A N/A 17.083±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000426 CIL_000426_0001 CGP 6:33299694-33317942

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IDA Golgi membrane
GO:0002397 IEA MHC class I protein complex assembly
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 IEA antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IEA protein binding
GO:0005783 TAS endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0006461 TAS protein complex assembly
GO:0006890 NAS retrograde vesicle-mediated transport, Golgi to ER
GO:0006952 IEA defense response
GO:0006955 TAS immune response
GO:0015433 TAS peptide antigen-transporting ATPase activity
GO:0015833 TAS peptide transport
GO:0016020 IEA membrane
GO:0016021 TAS integral component of membrane
GO:0019885 IEA antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0042288 TAS MHC class I protein binding
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 TAS peptide antigen binding
GO:0042824 IEA MHC class I peptide loading complex
GO:0042825 IDA TAP complex
GO:0042886 TAS amide transport
GO:0046978 IPI TAP1 binding
GO:0046979 IPI TAP2 binding
GO:0050823 IEA peptide antigen stabilization
GO:0051082 TAS unfolded protein binding
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045011 TAPBP (1 of 2) TAP binding protein (tapasin) protein_coding Danio_rerio
ENSDARG00000079402 tapbp TAP binding protein protein_coding Danio_rerio
ENSMUSG00000024308 Tapbp TAP binding protein protein_coding Mus_musculus

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