C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutathione peroxidase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000233276 GPX1 9606 - 3:49357176-49358600 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000419349 GPX1-002 49357178-49358283 protein_coding
  ENST00000419783 GPX1-001 49357176-49358600 protein_coding
  ENST00000496791 GPX1-003 49357608-49358325 processed_transcript
  ENST00000620890 GPX1-201 49357180-49358358 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000419349ENST00000419783ENST00000496791ENST00000620890
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000419349 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.434±0.00 N/A N/A N/A N/A
ENST00000419783 N/A N/A N/A N/A 2.034±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000496791 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 33.419±0.00 44.330±0.00 7.133±0.00
ENST00000620890 98.859±0.00 131.568±0.00 5.538±0.00 35.419±16.34 191.481±176.52 52.457±45.47 26.865±23.62 108.123±79.65 97.169±85.49 137.621±128.89 30.557±11.22 88.032±59.21 303.902±144.75 50.327±29.53

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000302 IEA response to reactive oxygen species
GO:0001659 IEA temperature homeostasis
GO:0001885 IEA endothelial cell development
GO:0002862 IEA negative regulation of inflammatory response to antigenic stimulus
GO:0004602 IDA:IEA glutathione peroxidase activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006195 TAS purine nucleotide catabolic process
GO:0006629 IEA lipid metabolic process
GO:0006641 IEA triglyceride metabolic process
GO:0006749 IDA glutathione metabolic process
GO:0006915 IEA apoptotic process
GO:0006979 IEA response to oxidative stress
GO:0006982 IEA response to lipid hydroperoxide
GO:0007568 IEA aging
GO:0007605 IEA sensory perception of sound
GO:0008283 IEA cell proliferation
GO:0008430 IEA selenium binding
GO:0008631 IEA intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009410 IEA response to xenobiotic stimulus
GO:0009609 IEA response to symbiotic bacterium
GO:0009611 IEA response to wounding
GO:0009636 IEA response to toxic substance
GO:0009650 IMP UV protection
GO:0009725 IEA response to hormone
GO:0009749 IEA response to glucose
GO:0010269 IMP response to selenium ion
GO:0010332 IEA response to gamma radiation
GO:0014070 IEA response to organic cyclic compound
GO:0014902 IEA myotube differentiation
GO:0017124 IPI SH3 domain binding
GO:0018158 IEA protein oxidation
GO:0019369 TAS arachidonic acid metabolic process
GO:0019372 TAS lipoxygenase pathway
GO:0032355 IEA response to estradiol
GO:0033194 IEA response to hydroperoxide
GO:0033599 IMP regulation of mammary gland epithelial cell proliferation
GO:0034599 NAS cellular response to oxidative stress
GO:0035094 IEA response to nicotine
GO:0040029 IDA regulation of gene expression, epigenetic
GO:0042311 IEA vasodilation
GO:0042542 IMP response to hydrogen peroxide
GO:0042744 IDA hydrogen peroxide catabolic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043295 IEA glutathione binding
GO:0043403 IEA skeletal muscle tissue regeneration
GO:0043523 IEA regulation of neuron apoptotic process
GO:0043534 IEA blood vessel endothelial cell migration
GO:0044281 TAS small molecule metabolic process
GO:0045444 IEA fat cell differentiation
GO:0045454 IDA cell redox homeostasis
GO:0047066 IEA phospholipid-hydroperoxide glutathione peroxidase activity
GO:0048741 IEA skeletal muscle fiber development
GO:0051450 IEA myoblast proliferation
GO:0051593 IEA response to folic acid
GO:0051702 IEA interaction with symbiont
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0060047 IMP heart contraction
GO:0060055 IEA angiogenesis involved in wound healing
GO:0061136 IDA regulation of proteasomal protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0090201 IMP negative regulation of release of cytochrome c from mitochondria
GO:0097413 IDA Lewy body
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902176 IEA negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1902905 ISS positive regulation of fibril organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000063856 Gpx1 glutathione peroxidase 1 protein_coding Mus_musculus

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