C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutathione peroxidase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000419349 GPX1-002 ENSG00000233276 9606 - 3:49357178-49358283 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungENST00000419349
Transcript ID Lung
ENST00000419349 1.434±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004602 IDA:IEA glutathione peroxidase activity
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006195 TAS purine nucleotide catabolic process
GO:0006749 IDA glutathione metabolic process
GO:0006979 IEA response to oxidative stress
GO:0009650 IMP UV protection
GO:0010269 IMP response to selenium ion
GO:0017124 IPI SH3 domain binding
GO:0019369 TAS arachidonic acid metabolic process
GO:0019372 TAS lipoxygenase pathway
GO:0033599 IMP regulation of mammary gland epithelial cell proliferation
GO:0034599 NAS cellular response to oxidative stress
GO:0040029 IDA regulation of gene expression, epigenetic
GO:0042542 IMP response to hydrogen peroxide
GO:0042744 IDA hydrogen peroxide catabolic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0045454 IDA cell redox homeostasis
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0060047 IMP heart contraction
GO:0061136 IDA regulation of proteasomal protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0090201 IMP negative regulation of release of cytochrome c from mitochondria
GO:0097413 IDA Lewy body
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902905 ISS positive regulation of fibril organization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000082429 Gpx1-201 protein_coding Mus_musculus 0 375

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