C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000239713 APOBEC3G 9606 + 22:39040961-39087743 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000407997 APOBEC3G-001 39077005-39087743 protein_coding
  ENST00000452957 APOBEC3G-201 39040961-39087421 protein_coding
  ENST00000461827 APOBEC3G-004 39077084-39083884 processed_transcript
  ENST00000463934 APOBEC3G-002 39077067-39079700 retained_intron
  ENST00000480000 APOBEC3G-005 39077079-39081687 retained_intron
  ENST00000481958 APOBEC3G-003 39080635-39083214 retained_intron
  ENST00000486357 APOBEC3G-006 39078512-39081194 processed_transcript
  ENST00000494150 APOBEC3G-007 39079662-39082679 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000407997ENST00000452957ENST00000461827ENST00000463934ENST00000480000ENST00000494150
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000407997 1.721±0.00 3.247±0.00 N/A 0.418±0.09 0.839±0.00 1.179±0.00 N/A 1.117±0.00 1.373±0.00 1.324±0.00 0.240±0.00 4.592±3.39 1.976±0.00 2.219±0.00
ENST00000452957 N/A N/A N/A N/A 1.426±0.00 1.416±0.00 N/A N/A N/A 3.322±0.99 0.576±0.00 4.600±0.00 1.290±0.00 3.451±0.00
ENST00000461827 N/A N/A N/A N/A N/A N/A 0.232±0.00 1.722±0.00 N/A N/A N/A N/A N/A N/A
ENST00000463934 N/A N/A N/A 0.612±0.00 N/A 1.212±0.25 0.580±0.00 N/A N/A 1.736±0.00 0.214±0.00 1.224±0.00 N/A N/A
ENST00000480000 N/A N/A N/A N/A N/A N/A 0.400±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000494150 N/A N/A 0.109±0.00 0.238±0.00 N/A 0.535±0.00 0.226±0.00 0.410±0.00 0.238±0.06 N/A N/A 0.683±0.00 N/A 1.365±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0002230 IDA positive regulation of defense response to virus by host
GO:0003723 IDA RNA binding
GO:0003824 IEA catalytic activity
GO:0004126 TAS cytidine deaminase activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0008270 IDA:IEA zinc ion binding
GO:0009972 IDA cytidine deamination
GO:0010529 IDA negative regulation of transposition
GO:0016032 TAS viral process
GO:0016553 TAS base conversion or substitution editing
GO:0016814 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO:0030529 IDA ribonucleoprotein complex
GO:0030895 TAS apolipoprotein B mRNA editing enzyme complex
GO:0042803 NAS protein homodimerization activity
GO:0045071 IDA negative regulation of viral genome replication
GO:0045087 IDA innate immune response
GO:0045869 IDA negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0047844 IDA deoxycytidine deaminase activity
GO:0048525 IDA negative regulation of viral process
GO:0051607 IDA defense response to virus
GO:0070383 IDA DNA cytosine deamination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000009585 Apobec3 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 protein_coding Mus_musculus

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