C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: toll-like receptor 9
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000239732 TLR9 9606 - 3:52221080-52226163 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360658 TLR9-001 52221080-52226163 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087C CIL_00087C_0001 VISTA 3:51705330-52307529
CIL_0008NT CIL_0008NT_0001 VISTA 3:51738719-52342071
CIL_0007WP CIL_0007WP_0001 VISTA 3:52127966-52731115

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002237 TAS response to molecule of bacterial origin
GO:0002755 IEA MyD88-dependent toll-like receptor signaling pathway
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005149 IPI interleukin-1 receptor binding
GO:0005515 IEA protein binding
GO:0005576 NAS extracellular region
GO:0005737 IDA cytoplasm
GO:0005764 ISS lysosome
GO:0005768 ISS endosome
GO:0005783 ISS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 IDA plasma membrane
GO:0006954 IEA inflammatory response
GO:0007165 IEA signal transduction
GO:0007252 IDA I-kappaB phosphorylation
GO:0008286 TAS insulin receptor signaling pathway
GO:0010008 TAS endosome membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0030277 ISS maintenance of gastrointestinal epithelium
GO:0032009 ISS early phagosome
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032715 ISS negative regulation of interleukin-6 production
GO:0032717 IDA negative regulation of interleukin-8 production
GO:0032722 IDA positive regulation of chemokine production
GO:0032728 ISS positive regulation of interferon-beta production
GO:0032733 ISS positive regulation of interleukin-10 production
GO:0032735 ISS positive regulation of interleukin-12 production
GO:0032741 ISS positive regulation of interleukin-18 production
GO:0032755 IDA positive regulation of interleukin-6 production
GO:0032757 IDA positive regulation of interleukin-8 production
GO:0032760 ISS positive regulation of tumor necrosis factor production
GO:0034122 IDA negative regulation of toll-like receptor signaling pathway
GO:0034123 IDA positive regulation of toll-like receptor signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0035197 IMP siRNA binding
GO:0036020 TAS endolysosome membrane
GO:0042346 IDA positive regulation of NF-kappaB import into nucleus
GO:0042742 NAS defense response to bacterium
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043507 IDA positive regulation of JUN kinase activity
GO:0045078 IDA positive regulation of interferon-gamma biosynthetic process
GO:0045087 TAS innate immune response
GO:0045356 IDA positive regulation of interferon-alpha biosynthetic process
GO:0045359 IDA positive regulation of interferon-beta biosynthetic process
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046330 IC positive regulation of JNK cascade
GO:0050707 IEA regulation of cytokine secretion
GO:0050729 IC positive regulation of inflammatory response
GO:0050829 IMP defense response to Gram-negative bacterium
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051770 ISS positive regulation of nitric-oxide synthase biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044490 tlr9 toll-like receptor 9 protein_coding Danio_rerio
ENSMUSG00000045322 Tlr9 toll-like receptor 9 protein_coding Mus_musculus

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