C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ciliary neurotrophic factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000242689 CNTF 9606 + 11:58622673-58625733 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361987 CNTF-001 58622673-58625733 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005127 TAS ciliary neurotrophic factor receptor binding
GO:0005138 IPI interleukin-6 receptor binding
GO:0005615 IC extracellular space
GO:0005737 IEA cytoplasm
GO:0007165 NAS signal transduction
GO:0008083 IDA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0040007 IEA growth
GO:0042517 IDA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043524 IDA negative regulation of neuron apoptotic process
GO:0046533 IEA negative regulation of photoreceptor cell differentiation
GO:0046668 IEA regulation of retinal cell programmed cell death
GO:0048644 IEA muscle organ morphogenesis
GO:0048666 IEA neuron development
GO:0070120 IDA ciliary neurotrophic factor-mediated signaling pathway
GO:0097058 IDA CRLF-CLCF1 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000079415 Cntf ciliary neurotrophic factor protein_coding Mus_musculus

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