C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ciliary neurotrophic factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361987 CNTF-001 ENSG00000242689 9606 + 11:58622673-58625733 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005127 TAS ciliary neurotrophic factor receptor binding
GO:0005138 IPI interleukin-6 receptor binding
GO:0005615 IC extracellular space
GO:0005737 IEA cytoplasm
GO:0007165 NAS signal transduction
GO:0008083 IDA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0040007 IEA growth
GO:0042517 IDA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043524 IDA negative regulation of neuron apoptotic process
GO:0046533 IEA negative regulation of photoreceptor cell differentiation
GO:0046668 IEA regulation of retinal cell programmed cell death
GO:0048644 IEA muscle organ morphogenesis
GO:0048666 IEA neuron development
GO:0070120 IDA ciliary neurotrophic factor-mediated signaling pathway
GO:0097058 IDA CRLF-CLCF1 complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112933 Cntf-001 protein_coding Mus_musculus 0 701
ENSMUST00000142247 Zfp91-003 nonsense_mediated_decay Mus_musculus 0 617

Loading