C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase A2, group IVB (cytosolic)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000243708 PLA2G4B 9606 + 15:41837775-41848147 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000452633 PLA2G4B-001 41837775-41848147 protein_coding
  ENST00000461382 PLA2G4B-002 41838813-41844530 retained_intron
  ENST00000483748 PLA2G4B-003 41841829-41848140 retained_intron
  ENST00000566076 PLA2G4B-006 41845881-41846700 retained_intron
  ENST00000569354 PLA2G4B-007 41846801-41848032 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005F8 CIL_0005F8_0001 CGP 15:41828085-41848155
CIL_0005F2 CIL_0005F2_0001 CGP 15:41828095-41848155

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004620 IEA phospholipase activity
GO:0004622 NAS lysophospholipase activity
GO:0005509 NAS calcium ion binding
GO:0005515 IEA protein binding
GO:0005544 NAS calcium-dependent phospholipid binding
GO:0005576 TAS extracellular region
GO:0005743 TAS mitochondrial inner membrane
GO:0005768 IEA endosome
GO:0005829 IDA cytosol
GO:0006644 TAS phospholipid metabolic process
GO:0006654 TAS phosphatidic acid biosynthetic process
GO:0006954 NAS inflammatory response
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0007567 NAS parturition
GO:0008152 IEA metabolic process
GO:0009395 IEA phospholipid catabolic process
GO:0019369 NAS arachidonic acid metabolic process
GO:0019722 NAS calcium-mediated signaling
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0036148 TAS phosphatidylglycerol acyl-chain remodeling
GO:0036150 TAS phosphatidylserine acyl-chain remodeling
GO:0036151 TAS phosphatidylcholine acyl-chain remodeling
GO:0036152 TAS phosphatidylethanolamine acyl-chain remodeling
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0046475 IDA glycerophospholipid catabolic process
GO:0047498 IDA calcium-dependent phospholipase A2 activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000033852 Gm28042 predicted gene, 28042 protein_coding Mus_musculus
ENSMUSG00000098488 Pla2g4b phospholipase A2, group IVB (cytosolic) protein_coding Mus_musculus

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