C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000244509 APOBEC3C 9606 + 22:39014083-39020352 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361441 APOBEC3C-001 39014083-39020352 protein_coding
  ENST00000428892 APOBEC3C-002 39014262-39018926 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361441ENST00000428892
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361441 9.026±0.00 22.165±0.00 0.183±0.00 0.836±0.77 5.357±3.27 6.460±5.55 4.513±3.85 1.959±1.79 2.068±0.45 5.609±3.41 N/A 12.792±9.58 7.071±1.51 16.981±4.30
ENST00000428892 N/A N/A 1.611±0.00 N/A N/A 1.107±0.00 N/A N/A 1.875±0.00 1.754±0.00 1.096±0.50 2.954±1.61 3.199±0.00 6.196±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0008270 IEA zinc ion binding
GO:0009972 IDA cytidine deamination
GO:0010529 IDA negative regulation of transposition
GO:0016032 IEA viral process
GO:0016814 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO:0044822 IDA poly(A) RNA binding
GO:0045071 IDA negative regulation of viral genome replication
GO:0045087 IEA innate immune response
GO:0051607 IEA defense response to virus
GO:0080111 IDA DNA demethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000009585 Apobec3 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 protein_coding Mus_musculus

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