C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 4A (Rodgers blood group)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000244731 C4A 9606 + 6:31982024-32002681 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000428956 C4A-001 31982024-32002681 protein_coding
  ENST00000460060 C4A-008 31997742-31999719 retained_intron
  ENST00000460841 C4A-005 31992177-31993976 retained_intron
  ENST00000463034 C4A-011 31999155-32002598 retained_intron
  ENST00000465724 C4A-012 32001127-32002255 retained_intron
  ENST00000467749 C4A-003 31982843-31983559 retained_intron
  ENST00000467948 C4A-004 31982881-31984398 processed_transcript
  ENST00000469975 C4A-002 32000998-32002664 retained_intron
  ENST00000470365 C4A-017 31997658-31999561 retained_intron
  ENST00000471624 C4A-009 31998851-31999530 retained_intron
  ENST00000477424 C4A-016 32001207-32001594 retained_intron
  ENST00000480795 C4A-015 31996517-31997396 retained_intron
  ENST00000483974 C4A-014 31994408-31995352 retained_intron
  ENST00000490663 C4A-007 32001260-32001868 retained_intron
  ENST00000491876 C4A-010 31999200-32002497 retained_intron
  ENST00000496659 C4A-006 31994581-31995627 retained_intron
  ENST00000498271 C4A-013 31982068-32002672 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryENST00000483974ENST00000498271
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary
ENST00000483974 N/A 5.802±0.00 N/A 6.588±0.00 N/A N/A 48.064±0.00 N/A 1.624±0.00 N/A
ENST00000498271 3.559±0.00 0.585±0.00 2.380±0.00 0.937±0.00 2.167±0.00 0.899±0.83 5.910±1.16 25.111±0.00 0.784±0.60 2.730±2.47

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001849 IDA complement component C1q binding
GO:0004866 IEA endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005886 TAS plasma membrane
GO:0006954 IEA inflammatory response
GO:0006956 IGI complement activation
GO:0006958 IEA complement activation, classical pathway
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030449 TAS regulation of complement activation
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle
GO:2000427 IGI positive regulation of apoptotic cell clearance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038424 si:dkey-8k3.2 complement component 4B (Chido blood group) protein_coding Danio_rerio
ENSMUSG00000073418 C4b complement component 4B (Chido blood group) protein_coding Mus_musculus

Loading