C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 4B (Chido blood group)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000073418 C4b 10090 - 17:34728380-34743882 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069507 C4b-001 34728380-34743882 protein_coding
  ENSMUST00000173057 C4b-003 34734365-34736099 nonsense_mediated_decay
  ENSMUST00000173669 C4b-002 34728380-34729265 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069507ENSMUST00000173669
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069507 79.950±39.49 16.485±3.16 21.444±0.57 3.035±4.27 62.257±14.44 9.609±1.84 6.654±2.35 1.742±0.77 147.780±127.09 57.191±5.93 1.365±0.77 13.397±3.73 4.422±5.67 0.733±0.19
ENSMUST00000173669 N/A N/A N/A 0.007±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.221±0.17 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000424 CIL_000424_0002 CGP 17:34728380-34804561

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004866 IEA endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0006954 IEA inflammatory response
GO:0006958 IEA complement activation, classical pathway
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0045087 IEA innate immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038424 si:dkey-8k3.2 complement component 4B (Chido blood group) protein_coding Danio_rerio
ENSG00000224389 C4B complement component 4B (Chido blood group) protein_coding Homo_sapiens
ENSG00000244731 C4A complement component 4A (Rodgers blood group) protein_coding Homo_sapiens

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