C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family, apoptosis inhibitory protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000249437 NAIP 9606 - 5:70968483-71025114 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000194097 NAIP-201 70968483-71020910 protein_coding
  ENST00000315147 NAIP-004 70968483-70987150 retained_intron
  ENST00000447012 NAIP-008 71002930-71011772 nonsense_mediated_decay
  ENST00000503719 NAIP-202 70968483-71024373 protein_coding
  ENST00000508426 NAIP-006 70970050-71020710 protein_coding
  ENST00000508794 NAIP-003 70998121-71020774 retained_intron
  ENST00000514857 NAIP-007 70970247-70976228 protein_coding
  ENST00000517649 NAIP-001 70968483-71024687 protein_coding
  ENST00000519014 NAIP-005 71003598-71020730 nonsense_mediated_decay
  ENST00000523981 NAIP-002 70969820-71025114 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000194097ENST00000315147ENST00000447012ENST00000508426ENST00000519014
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000194097 N/A N/A N/A N/A 0.591±0.00 N/A 0.102±0.00 0.189±0.00 N/A N/A N/A N/A 0.952±0.18 N/A
ENST00000315147 0.629±0.00 2.448±0.00 0.914±0.00 0.834±0.06 1.082±0.22 0.836±0.71 0.361±0.23 0.504±0.03 0.664±0.51 1.447±0.55 0.137±0.03 1.204±0.88 0.165±0.00 1.682±0.81
ENST00000447012 1.123±0.00 3.369±0.00 4.274±0.00 3.301±0.00 3.213±0.84 2.415±1.29 1.387±0.00 1.752±0.00 N/A 1.535±0.00 N/A 1.587±0.00 N/A 1.837±0.00
ENST00000508426 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.600±0.00 N/A N/A
ENST00000519014 1.052±0.00 N/A N/A 1.417±0.00 1.555±0.00 2.152±0.00 0.411±0.00 N/A 1.990±0.00 2.585±0.00 0.136±0.00 0.521±0.00 3.743±1.92 2.844±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004ZC CIL_0004ZC_0001 CGP 5:70925030-71025114
CIL_0004ZF CIL_0004ZF_0001 CGP 5:70968483-71067689

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IMP ATP binding
GO:0005737 ISS cytoplasm
GO:0006954 IEA inflammatory response
GO:0007399 TAS nervous system development
GO:0016323 ISS basolateral plasma membrane
GO:0043027 IEA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043524 TAS negative regulation of neuron apoptotic process
GO:0045087 IEA innate immune response
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021640 Naip1 NLR family, apoptosis inhibitory protein 1 protein_coding Mus_musculus
ENSMUSG00000071203 Naip5 NLR family, apoptosis inhibitory protein 5 protein_coding Mus_musculus
ENSMUSG00000078942 Naip6 NLR family, apoptosis inhibitory protein 6 protein_coding Mus_musculus
ENSMUSG00000078945 Naip2 NLR family, apoptosis inhibitory protein 2 protein_coding Mus_musculus

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