C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NADPH oxidase, EF-hand calcium binding domain 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000255346 NOX5 9606 + 15:68930525-69062743 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260364 NOX5-010 68930525-69062743 protein_coding
  ENST00000388866 NOX5-003 69014695-69057161 protein_coding
  ENST00000448182 NOX5-011 68930525-69056733 protein_coding
  ENST00000455873 NOX5-012 68930634-69056725 protein_coding
  ENST00000525143 NOX5-006 69031793-69056696 nonsense_mediated_decay
  ENST00000525163 NOX5-007 69045958-69049058 processed_transcript
  ENST00000527315 NOX5-005 69014732-69057122 retained_intron
  ENST00000529367 NOX5-008 69047089-69055500 retained_intron
  ENST00000530406 NOX5-004 69014698-69056733 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryENST00000260364ENST00000527315ENST00000529367
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary
ENST00000260364 N/A 0.025±0.00 0.006±0.00 N/A 0.025±0.00 N/A N/A N/A N/A 0.058±0.03
ENST00000527315 0.050±0.00 0.078±0.00 N/A 0.088±0.00 0.092±0.00 0.065±0.00 0.054±0.00 0.042±0.00 0.108±0.04 0.132±0.11
ENST00000529367 N/A N/A N/A N/A N/A N/A N/A 0.083±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00080E CIL_00080E_0001 VISTA 15:68398610-69001346
CIL_0008FN CIL_0008FN_0001 VISTA 15:68430786-69031787

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000910 NAS cytokinesis
GO:0001525 IEA angiogenesis
GO:0001935 IDA endothelial cell proliferation
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0006915 NAS apoptotic process
GO:0008283 NAS cell proliferation
GO:0010155 NAS regulation of proton transport
GO:0015252 IDA hydrogen ion channel activity
GO:0015992 IDA proton transport
GO:0016021 IEA integral component of membrane
GO:0016175 IDA superoxide-generating NADPH oxidase activity
GO:0016491 IEA oxidoreductase activity
GO:0020037 NAS heme binding
GO:0042554 IDA superoxide anion generation
GO:0043012 NAS regulation of fusion of sperm to egg plasma membrane
GO:0050660 NAS flavin adenine dinucleotide binding
GO:0050661 NAS NADP binding
GO:0050663 NAS cytokine secretion
GO:0055114 IDA:IEA oxidation-reduction process
GO:2000379 IDA positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079773 NOX5 NADPH oxidase, EF-hand calcium binding domain 5 protein_coding Danio_rerio

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