C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 2, subfamily A, polypeptide 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000255974 CYP2A6 9606 - 19:40843538-40882210 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301141 CYP2A6-001 40843538-40850447 protein_coding
  ENST00000596719 CYP2A6-003 40844922-40850440 retained_intron
  ENST00000599960 CYP2A6-004 40843541-40844852 retained_intron
  ENST00000600495 CYP2A6-002 40846029-40850447 nonsense_mediated_decay
  ENST00000610301 CYP2A6-201 40843796-40882210 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000301141ENST00000596719ENST00000599960ENST00000610301
Transcript ID Adipose Adrenal Brain Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000301141 0.081±0.00 N/A N/A N/A N/A 117.905±0.00 150.949±0.00 0.071±0.00 N/A N/A N/A
ENST00000596719 0.199±0.00 0.304±0.00 0.034±0.00 0.059±0.00 0.028±0.00 62.339±0.00 38.188±0.00 0.280±0.00 0.175±0.19 N/A 0.271±0.00
ENST00000599960 0.382±0.00 N/A N/A N/A N/A N/A 40.947±40.60 0.432±0.00 0.617±0.00 0.257±0.00 N/A
ENST00000610301 N/A N/A N/A N/A N/A N/A N/A N/A 0.240±0.00 0.151±0.06 0.014±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007H6 CIL_0007H6_0009 CGP 19:40843538-40882752

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005881 IDA cytoplasmic microtubule
GO:0006805 TAS xenobiotic metabolic process
GO:0008202 IMP steroid metabolic process
GO:0008389 IDA coumarin 7-hydroxylase activity
GO:0009804 IDA coumarin metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0017144 IMP drug metabolic process
GO:0019899 IPI enzyme binding
GO:0020037 IDA:IEA heme binding
GO:0042738 IDA exogenous drug catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046226 IDA coumarin catabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007173 cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 protein_coding Danio_rerio
ENSDARG00000068493 si:zfos-411a11.2 si:zfos-411a11.2 protein_coding Danio_rerio
ENSMUSG00000005547 Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 protein_coding Mus_musculus
ENSMUSG00000060407 Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 protein_coding Mus_musculus
ENSMUSG00000074254 Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 protein_coding Mus_musculus
ENSMUSG00000091867 Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 protein_coding Mus_musculus

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