C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: general transcription factor IIi
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000263001 GTF2I 9606 + 7:74657667-74760692 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000432143 GTF2I-019 74684657-74699041 protein_coding
  ENST00000438130 GTF2I-012 74744344-74749452 processed_transcript
  ENST00000443166 GTF2I-004 74658031-74717066 protein_coding
  ENST00000462915 GTF2I-010 74738023-74740071 processed_transcript
  ENST00000464471 GTF2I-016 74753845-74755878 retained_intron
  ENST00000473333 GTF2I-013 74744746-74746253 retained_intron
  ENST00000476035 GTF2I-014 74746056-74749396 retained_intron
  ENST00000482232 GTF2I-015 74752090-74754540 retained_intron
  ENST00000484840 GTF2I-007 74716612-74730289 retained_intron
  ENST00000490431 GTF2I-021 74705177-74714944 retained_intron
  ENST00000491325 GTF2I-008 74728003-74735513 processed_transcript
  ENST00000573035 GTF2I-001 74657685-74760692 protein_coding
  ENST00000613513 GTF2I-018 74657667-74691108 processed_transcript
  ENST00000614048 GTF2I-006 74755240-74759959 retained_intron
  ENST00000614986 GTF2I-002 74657758-74760692 protein_coding
  ENST00000615596 GTF2I-009 74733596-74738119 retained_intron
  ENST00000620631 GTF2I-011 74732537-74744941 processed_transcript
  ENST00000620879 GTF2I-017 74657758-74760692 protein_coding
  ENST00000621040 GTF2I-005 74754096-74760690 retained_intron
  ENST00000621640 GTF2I-022 74736503-74743882 retained_intron
  ENST00000621734 GTF2I-003 74657758-74760692 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000432143ENST00000443166ENST00000482232ENST00000491325ENST00000573035ENST00000614986ENST00000620879ENST00000621734
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000432143 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 26.077±0.00 N/A 18.008±0.00
ENST00000443166 20.390±0.00 14.085±0.00 18.947±0.00 13.984±0.82 24.467±3.14 18.504±7.23 13.454±0.00 19.437±0.00 13.369±6.13 16.300±5.88 21.114±0.00 19.853±6.27 18.218±0.83 15.701±1.15
ENST00000482232 N/A 9.388±0.00 N/A 9.956±0.00 N/A N/A N/A N/A N/A 5.316±0.00 N/A 6.964±0.00 N/A N/A
ENST00000491325 N/A N/A 27.616±0.00 14.553±0.00 27.746±6.49 11.474±0.00 N/A 22.075±0.00 15.934±8.26 19.849±0.00 21.594±0.00 15.470±2.68 21.192±0.00 16.119±0.00
ENST00000573035 N/A N/A N/A 1.162±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000614986 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.335±0.45 N/A N/A
ENST00000620879 N/A N/A N/A N/A N/A N/A N/A N/A 1.833±0.00 N/A N/A 1.535±0.50 N/A N/A
ENST00000621734 N/A N/A N/A 1.133±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0014886 IEA transition between slow and fast fiber
GO:0016020 IDA membrane
GO:0016525 IDA negative regulation of angiogenesis
GO:0042995 IEA cell projection
GO:0043025 IEA neuronal cell body
GO:0051019 IEA mitogen-activated protein kinase binding
GO:0051481 IEA negative regulation of cytosolic calcium ion concentration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022203 gtf2ird1 GTF2I repeat domain-containing 1 protein_coding Danio_rerio
ENSMUSG00000060261 Gtf2i general transcription factor II I protein_coding Mus_musculus

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