C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: OTU deubiquitinase 7B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000264522 OTUD7B 9606 - 1:149937812-150010676 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000417191 OTUD7B-003 149947291-150010675 protein_coding
  ENST00000581312 OTUD7B-001 149937812-150010676 protein_coding
  ENST00000619871 OTUD7B-002 149960927-149971261 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000417191ENST00000581312ENST00000619871
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000417191 N/A N/A 1.496±0.00 2.059±0.00 N/A 2.071±0.00 N/A 0.910±0.00 3.867±0.00 N/A 2.972±0.00 N/A N/A 7.428±0.00
ENST00000581312 3.541±0.00 1.419±0.00 N/A 14.188±0.00 4.037±3.44 1.632±1.17 4.165±0.00 2.355±0.00 0.987±0.35 1.822±0.53 7.052±0.00 2.801±0.99 1.933±0.77 2.361±0.06
ENST00000619871 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.398±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0002385 ISS mucosal immune response
GO:0003677 IEA DNA binding
GO:0004221 ISS ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0008234 ISS cysteine-type peptidase activity
GO:0008270 IEA zinc ion binding
GO:0016579 IEA protein deubiquitination
GO:0032717 IDA negative regulation of interleukin-8 production
GO:0035871 IDA protein K11-linked deubiquitination
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0070530 IEA K63-linked polyubiquitin binding
GO:0070536 IDA protein K63-linked deubiquitination
GO:0071108 ISS protein K48-linked deubiquitination
GO:1900181 IDA negative regulation of protein localization to nucleus
GO:1990380 IDA Lys48-specific deubiquitinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017220 otud7b OTU domain containing 7B protein_coding Danio_rerio
ENSMUSG00000038495 Otud7b OTU domain containing 7B protein_coding Mus_musculus

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