C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: OTU domain containing 7B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038495 Otud7b 10090 + 3:96104527-96161129 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035519 Otud7b-201 96104527-96161129 protein_coding
  ENSMUST00000090785 Otud7b-001 96104527-96161129 protein_coding
  ENSMUST00000098849 Otud7b-002 96107087-96161129 protein_coding
  ENSMUST00000132980 Otud7b-004 96104527-96141518 protein_coding
  ENSMUST00000135263 Otud7b-006 96150704-96152563 processed_transcript
  ENSMUST00000138206 Otud7b-003 96104527-96144325 protein_coding
  ENSMUST00000146660 Otud7b-005 96104548-96141553 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035519ENSMUST00000090785ENSMUST00000098849ENSMUST00000138206ENSMUST00000146660
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035519 2.598±1.42 4.433±0.79 4.925±0.32 1.358±0.19 2.645±1.15 3.107±1.25 2.365±0.37 3.227±1.44 2.221±0.60 9.754±1.94 3.501±0.00 4.214±1.23 3.962±2.57 4.541±2.06
ENSMUST00000090785 1.041±0.00 N/A N/A 2.127±0.00 N/A 1.230±0.00 0.792±0.30 0.654±0.02 0.556±0.26 N/A N/A 1.043±0.00 N/A N/A
ENSMUST00000098849 N/A 1.334±0.00 N/A 0.670±0.00 N/A N/A 0.848±0.00 N/A N/A N/A N/A N/A N/A 5.223±0.10
ENSMUST00000138206 N/A 6.711±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000146660 N/A 9.156±1.40 N/A N/A 7.601±0.00 N/A N/A N/A N/A N/A N/A 13.467±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005V1 CIL_0005V1_0002 CGP 3:96104527-96171718

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0002385 IMP mucosal immune response
GO:0003677 IEA DNA binding
GO:0004221 IDA ubiquitin thiolesterase activity
GO:0004843 ISS ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0008234 IMP cysteine-type peptidase activity
GO:0008270 IEA zinc ion binding
GO:0016579 IDA protein deubiquitination
GO:0032717 IEA negative regulation of interleukin-8 production
GO:0035871 ISS protein K11-linked deubiquitination
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0070530 IDA K63-linked polyubiquitin binding
GO:0070536 ISS protein K63-linked deubiquitination
GO:0071108 IMP protein K48-linked deubiquitination
GO:1900181 IEA negative regulation of protein localization to nucleus
GO:1990380 IEA Lys48-specific deubiquitinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017220 otud7b OTU domain containing 7B protein_coding Danio_rerio
ENSG00000264522 OTUD7B OTU deubiquitinase 7B protein_coding Homo_sapiens

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