C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific methyltransferase 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000272333 KMT2B 9606 + 19:35718019-35738878 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000420124 KMT2B-001 35718019-35738878 protein_coding
  ENST00000585476 KMT2B-004 35735220-35738878 retained_intron
  ENST00000586308 KMT2B-005 35737468-35738496 retained_intron
  ENST00000592092 KMT2B-006 35733258-35737156 retained_intron
  ENST00000606995 KMT2B-008 35720902-35721529 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000420124
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000420124 6.085±0.00 13.746±0.00 0.789±0.00 4.605±0.00 2.991±1.83 3.020±2.16 3.902±0.00 4.937±4.43 2.306±1.05 10.480±0.00 4.643±4.04 10.430±6.14 7.295±1.08 21.973±5.26

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001541 IEA ovarian follicle development
GO:0003677 IEA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0009994 IEA oocyte differentiation
GO:0016458 IEA gene silencing
GO:0030728 IEA ovulation
GO:0034968 IEA histone lysine methylation
GO:0035097 IDA:IEA histone methyltransferase complex
GO:0042800 IDA:IEA histone methyltransferase activity (H3-K4 specific)
GO:0048096 NAS chromatin-mediated maintenance of transcription
GO:0051568 IMP:IEA histone H3-K4 methylation
GO:0051569 IEA regulation of histone H3-K4 methylation
GO:0080182 IEA histone H3-K4 trimethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060697 kmt2bb lysine (K)-specific methyltransferase 2Bb protein_coding Danio_rerio
ENSDARG00000062962 kmt2ba lysine (K)-specific methyltransferase 2Ba protein_coding Danio_rerio
ENSMUSG00000006307 Kmt2b lysine (K)-specific methyltransferase 2B protein_coding Mus_musculus

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