C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific methyltransferase 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006307 Kmt2b 10090 - 7:30568858-30588726 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006470 Kmt2b-003 30568858-30588717 protein_coding
  ENSMUST00000108154 Kmt2b-001 30568858-30588726 protein_coding
  ENSMUST00000125372 Kmt2b-004 30584281-30585074 processed_transcript
  ENSMUST00000125836 Kmt2b-008 30577030-30578994 processed_transcript
  ENSMUST00000128456 Kmt2b-006 30573169-30574174 retained_intron
  ENSMUST00000131002 Kmt2b-002 30568860-30585340 protein_coding
  ENSMUST00000136959 Kmt2b-007 30569753-30570664 retained_intron
  ENSMUST00000152931 Kmt2b-005 30575573-30577164 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006470ENSMUST00000108154ENSMUST00000131002ENSMUST00000152931
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006470 4.628±1.11 6.582±0.60 3.714±0.60 8.230±1.57 7.847±2.70 6.037±0.99 2.371±0.82 3.198±0.32 2.451±0.75 7.885±0.78 2.789±0.26 6.753±1.61 4.704±2.39 4.063±1.63
ENSMUST00000108154 N/A N/A N/A N/A N/A 1.661±0.00 N/A N/A N/A N/A N/A 2.382±0.00 N/A N/A
ENSMUST00000131002 6.902±1.92 9.422±1.65 5.769±2.01 10.422±1.49 5.741±2.53 6.437±2.01 2.533±0.46 2.603±1.01 2.663±1.10 5.267±0.42 1.659±0.45 11.049±3.80 6.215±2.72 10.665±4.67
ENSMUST00000152931 N/A N/A N/A N/A 19.190±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006V0 CIL_0006V0_0002 CGP 7:30565427-30588726

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001541 IMP ovarian follicle development
GO:0003677 IEA DNA binding
GO:0005634 ISO nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0009994 IMP oocyte differentiation
GO:0016458 IMP gene silencing
GO:0030728 IMP ovulation
GO:0034968 IMP histone lysine methylation
GO:0035097 ISO histone methyltransferase complex
GO:0042800 ISO histone methyltransferase activity (H3-K4 specific)
GO:0051569 IMP regulation of histone H3-K4 methylation
GO:0080182 IMP histone H3-K4 trimethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060697 kmt2bb lysine (K)-specific methyltransferase 2Bb protein_coding Danio_rerio
ENSDARG00000062962 kmt2ba lysine (K)-specific methyltransferase 2Ba protein_coding Danio_rerio
ENSG00000272333 KMT2B lysine (K)-specific methyltransferase 2B protein_coding Homo_sapiens

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