C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide-3-kinase, regulatory subunit 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000276231 PIK3R6 9606 - 17:8802723-8867677 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000611951 PIK3R6-003 8802737-8867660 nonsense_mediated_decay
  ENST00000613555 PIK3R6-001 8802723-8867677 nonsense_mediated_decay
  ENST00000614407 PIK3R6-002 8803273-8849794 protein_coding
  ENST00000619866 PIK3R6-201 8802737-8867677 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000611951ENST00000613555ENST00000614407ENST00000619866
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000611951 N/A N/A N/A N/A 0.215±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000613555 N/A N/A N/A N/A N/A N/A N/A 0.020±0.00 N/A N/A 0.016±0.00 0.183±0.00 N/A
ENST00000614407 N/A N/A 0.030±0.00 0.021±0.00 0.100±0.00 N/A N/A N/A 0.249±0.00 N/A N/A 0.076±0.00 0.847±0.00
ENST00000619866 0.054±0.00 1.437±0.00 N/A 0.039±0.00 0.235±0.00 0.033±0.02 0.146±0.00 0.037±0.00 0.044±0.00 0.453±0.00 0.344±0.17 0.302±0.15 0.667±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AZ CIL_0009AZ_0001 VISTA 17:8380027-8982000
CIL_00088C CIL_00088C_0001 VISTA 17:8397056-8997791

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005944 IEA phosphatidylinositol 3-kinase complex, class IB
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0016020 ISS membrane
GO:0030168 TAS platelet activation
GO:0043406 ISS positive regulation of MAP kinase activity
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0044281 TAS small molecule metabolic process
GO:0045766 IMP positive regulation of angiogenesis
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046934 ISS phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0046935 IEA 1-phosphatidylinositol-3-kinase regulator activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088026 PIK3R6 (1 of 2) phosphoinositide-3-kinase, regulatory subunit 6 protein_coding Danio_rerio
ENSDARG00000091140 pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 protein_coding Danio_rerio
ENSMUSG00000046207 Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 protein_coding Mus_musculus

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