C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide-3-kinase, regulatory subunit 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000046207 Pik3r6 10090 + 11:68503019-68552698 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000060441 Pik3r6-201 68503019-68552698 protein_coding
  ENSMUST00000102613 Pik3r6-001 68503019-68552698 protein_coding
  ENSMUST00000126069 Pik3r6-003 68536200-68544383 processed_transcript
  ENSMUST00000131669 Pik3r6-004 68552064-68552696 processed_transcript
  ENSMUST00000153671 Pik3r6-002 68503091-68552698 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000060441ENSMUST00000102613ENSMUST00000131669ENSMUST00000153671
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000060441 2.340±1.66 0.902±0.06 0.580±0.09 0.628±0.01 2.340±0.85 0.378±0.23 2.327±0.43 1.248±0.27 0.608±0.43 3.794±1.08 0.518±0.18 1.322±0.41 0.361±0.02 1.890±0.18
ENSMUST00000102613 1.119±0.50 N/A 0.276±0.04 0.193±0.00 0.544±0.00 0.514±0.29 N/A 0.618±0.31 0.235±0.13 1.240±0.17 0.308±0.00 0.672±0.32 0.495±0.49 0.716±0.16
ENSMUST00000131669 N/A N/A N/A 0.949±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.081±0.00
ENSMUST00000153671 0.695±0.16 0.460±0.00 0.271±0.04 0.238±0.11 0.939±0.23 0.131±0.00 0.646±0.16 0.240±0.00 0.138±0.08 N/A 0.281±0.01 0.612±0.00 0.270±0.05 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088C CIL_00088C_0002 VISTA 11:68323475-68924174
CIL_0009AZ CIL_0009AZ_0002 VISTA 11:68337699-68940744
CIL_00033Z CIL_00033Z_0002 CGP 11:68503019-68558245

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005515 IEA protein binding
GO:0005944 IDA phosphatidylinositol 3-kinase complex, class IB
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0016020 IDA membrane
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0045766 ISS positive regulation of angiogenesis
GO:0046854 IDA phosphatidylinositol phosphorylation
GO:0046934 IDA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0046935 IDA 1-phosphatidylinositol-3-kinase regulator activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088026 PIK3R6 (1 of 2) phosphoinositide-3-kinase, regulatory subunit 6 protein_coding Danio_rerio
ENSDARG00000091140 pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 protein_coding Danio_rerio
ENSG00000276231 PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 protein_coding Homo_sapiens

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