C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000277807 LILRB1 9606 + CHR_HSCHR19LRC_PGF1_CTG3_1:54504396-54631214 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000612271 LILRB1-007 54563637-54564694 retained_intron
  ENST00000612335 LILRB1-211 54561585-54567530 protein_coding
  ENST00000612636 LILRB1-002 54561585-54567389 protein_coding
  ENST00000614951 LILRB1-212 54504396-54564629 protein_coding
  ENST00000615064 LILRB1-005 54563654-54568039 retained_intron
  ENST00000615492 LILRB1-008 54564882-54566127 retained_intron
  ENST00000616565 LILRB1-213 54561028-54568039 protein_coding
  ENST00000617686 LILRB1-004 54561023-54567688 protein_coding
  ENST00000618055 LILRB1-001 54547681-54568080 protein_coding
  ENST00000618681 LILRB1-003 54561018-54568039 protein_coding
  ENST00000619000 LILRB1-006 54563634-54564759 retained_intron
  ENST00000620234 LILRB1-214 54561585-54631214 protein_coding
  ENST00000621463 LILRB1-009 54563207-54564002 retained_intron

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001915 IDA negative regulation of T cell mediated cytotoxicity
GO:0002230 IDA positive regulation of defense response to virus by host
GO:0002309 IDA T cell proliferation involved in immune response
GO:0002740 IDA negative regulation of cytokine secretion involved in immune response
GO:0002767 NAS immune response-inhibiting cell surface receptor signaling pathway
GO:0002774 IDA Fc receptor mediated inhibitory signaling pathway
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0007165 IDA signal transduction
GO:0008157 IPI protein phosphatase 1 binding
GO:0009615 IDA response to virus
GO:0009897 IDA external side of plasma membrane
GO:0010628 IDA positive regulation of gene expression
GO:0014063 IDA negative regulation of serotonin secretion
GO:0016021 IEA integral component of membrane
GO:0030107 IDA HLA-A specific inhibitory MHC class I receptor activity
GO:0030109 IDA HLA-B specific inhibitory MHC class I receptor activity
GO:0031623 TAS receptor internalization
GO:0032393 IDA MHC class I receptor activity
GO:0032609 IDA interferon-gamma production
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032945 IDA negative regulation of mononuclear cell proliferation
GO:0035548 IDA negative regulation of interferon-beta secretion
GO:0042130 IDA negative regulation of T cell proliferation
GO:0042169 IDA SH2 domain binding
GO:0042288 IPI MHC class I protein binding
GO:0042536 IDA negative regulation of tumor necrosis factor biosynthetic process
GO:0042803 IPI protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0045077 IDA negative regulation of interferon-gamma biosynthetic process
GO:0045786 IDA negative regulation of cell cycle
GO:0045806 IDA negative regulation of endocytosis
GO:0045919 IDA positive regulation of cytolysis
GO:0045944 NAS positive regulation of transcription from RNA polymerase II promoter
GO:0045953 IDA negative regulation of natural killer cell mediated cytotoxicity
GO:0046636 IDA negative regulation of alpha-beta T cell activation
GO:0050776 TAS regulation of immune response
GO:0051607 IDA defense response to virus
GO:0051926 IDA negative regulation of calcium ion transport
GO:0071222 IEP cellular response to lipopolysaccharide
GO:0072643 IDA interferon-gamma secretion
GO:0097028 IEP dendritic cell differentiation
GO:2000669 IDA negative regulation of dendritic cell apoptotic process
GO:2001180 IDA negative regulation of interleukin-10 secretion
GO:2001183 IDA negative regulation of interleukin-12 secretion
GO:2001186 IDA negative regulation of CD8-positive, alpha-beta T cell activation
GO:2001189 IDA negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:2001193 IDA positive regulation of gamma-delta T cell activation involved in immune response
GO:2001199 IMP negative regulation of dendritic cell differentiation
GO:2001202 IDA negative regulation of transforming growth factor-beta secretion
GO:2001205 IDA negative regulation of osteoclast development

Homologs

No Homologs available.

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