C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000618055 LILRB1-001 ENSG00000277807 9606 + CHR_HSCHR19LRC_PGF1_CTG3_1:54547681-54568080 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001915 IDA negative regulation of T cell mediated cytotoxicity
GO:0002230 IDA positive regulation of defense response to virus by host
GO:0002309 IDA T cell proliferation involved in immune response
GO:0002740 IDA negative regulation of cytokine secretion involved in immune response
GO:0002767 NAS immune response-inhibiting cell surface receptor signaling pathway
GO:0002774 IDA Fc receptor mediated inhibitory signaling pathway
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0007165 IDA signal transduction
GO:0008157 IPI protein phosphatase 1 binding
GO:0009615 IDA response to virus
GO:0009897 IDA external side of plasma membrane
GO:0010628 IDA positive regulation of gene expression
GO:0014063 IDA negative regulation of serotonin secretion
GO:0016021 IEA integral component of membrane
GO:0030107 IDA HLA-A specific inhibitory MHC class I receptor activity
GO:0030109 IDA HLA-B specific inhibitory MHC class I receptor activity
GO:0031623 TAS receptor internalization
GO:0032393 IDA MHC class I receptor activity
GO:0032609 IDA interferon-gamma production
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032945 IDA negative regulation of mononuclear cell proliferation
GO:0035548 IDA negative regulation of interferon-beta secretion
GO:0042130 IDA negative regulation of T cell proliferation
GO:0042169 IDA SH2 domain binding
GO:0042288 IPI MHC class I protein binding
GO:0042536 IDA negative regulation of tumor necrosis factor biosynthetic process
GO:0042803 IPI protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0045077 IDA negative regulation of interferon-gamma biosynthetic process
GO:0045786 IDA negative regulation of cell cycle
GO:0045806 IDA negative regulation of endocytosis
GO:0045919 IDA positive regulation of cytolysis
GO:0045944 NAS positive regulation of transcription from RNA polymerase II promoter
GO:0045953 IDA negative regulation of natural killer cell mediated cytotoxicity
GO:0046636 IDA negative regulation of alpha-beta T cell activation
GO:0050776 TAS regulation of immune response
GO:0051607 IDA defense response to virus
GO:0051926 IDA negative regulation of calcium ion transport
GO:0071222 IEP cellular response to lipopolysaccharide
GO:0072643 IDA interferon-gamma secretion
GO:0097028 IEP dendritic cell differentiation
GO:2000669 IDA negative regulation of dendritic cell apoptotic process
GO:2001180 IDA negative regulation of interleukin-10 secretion
GO:2001183 IDA negative regulation of interleukin-12 secretion
GO:2001186 IDA negative regulation of CD8-positive, alpha-beta T cell activation
GO:2001189 IDA negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:2001193 IDA positive regulation of gamma-delta T cell activation involved in immune response
GO:2001199 IMP negative regulation of dendritic cell differentiation
GO:2001202 IDA negative regulation of transforming growth factor-beta secretion
GO:2001205 IDA negative regulation of osteoclast development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000070639 Gm14548-001 protein_coding Mus_musculus 1e-25 122

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