C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dopamine beta hydroxylase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000889 Dbh 10090 + 2:27165233-27183200 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000910 Dbh-001 27165233-27183200 protein_coding
  ENSMUST00000155290 Dbh-002 27177093-27177372 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000000910
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000000910 133.161±9.74 0.106±0.08 0.389±0.33 0.038±0.02 2.749±0.63 0.532±0.00 2.252±1.18 0.010±0.01 0.077±0.03 0.180±0.09 0.003±0.00 0.052±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014W CIL_00014W_0002 CGP 2:27110380-27183200
CIL_00014X CIL_00014X_0002 CGP 2:27165233-27248337

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IMP cytokine production
GO:0001974 IMP blood vessel remodeling
GO:0001975 IMP response to amphetamine
GO:0002443 IMP leukocyte mediated immunity
GO:0004500 IEA dopamine beta-monooxygenase activity
GO:0005507 IEA copper ion binding
GO:0007613 IMP memory
GO:0007626 IMP locomotory behavior
GO:0008306 IMP associative learning
GO:0008542 IMP visual learning
GO:0016021 IEA integral component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0031418 IEA L-ascorbic acid binding
GO:0042127 IMP regulation of cell proliferation
GO:0042309 IMP homoiothermy
GO:0042420 IMP dopamine catabolic process
GO:0042421 IEA norepinephrine biosynthetic process
GO:0042593 IMP glucose homeostasis
GO:0042596 IMP fear response
GO:0042711 IMP maternal behavior
GO:0045907 IMP positive regulation of vasoconstriction
GO:0048149 IMP behavioral response to ethanol
GO:0048265 IMP response to pain
GO:0050900 IMP leukocyte migration
GO:0055114 IEA oxidation-reduction process
GO:2001236 IMP regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069446 dbh dopamine beta hydroxylase protein_coding Danio_rerio
ENSG00000123454 DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) protein_coding Homo_sapiens

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