C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001034 Mapk7 10090 - 11:61488812-61494406 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000079080 Mapk7-011 61488812-61494296 protein_coding
  ENSMUST00000101085 Mapk7-013 61488812-61494266 protein_coding
  ENSMUST00000108714 Mapk7-012 61488812-61494296 protein_coding
  ENSMUST00000123360 Mapk7-008 61491606-61494266 processed_transcript
  ENSMUST00000125840 Mapk7-002 61488812-61494296 processed_transcript
  ENSMUST00000126495 Mapk7-004 61491302-61493705 processed_transcript
  ENSMUST00000128478 Mapk7-014 61488812-61494266 processed_transcript
  ENSMUST00000129272 Mapk7-009 61491556-61494266 processed_transcript
  ENSMUST00000135521 Mapk7-003 61491596-61494406 processed_transcript
  ENSMUST00000139663 Mapk7-007 61491578-61494266 processed_transcript
  ENSMUST00000139932 Mapk7-006 61491606-61494188 processed_transcript
  ENSMUST00000140779 Mapk7-005 61491642-61494188 processed_transcript
  ENSMUST00000152755 Mapk7-001 61488812-61494266 processed_transcript
  ENSMUST00000153441 Mapk7-010 61489459-61490938 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000079080ENSMUST00000108714ENSMUST00000125840ENSMUST00000128478ENSMUST00000152755ENSMUST00000153441
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000079080 8.907±0.01 6.319±1.58 11.560±1.28 29.559±7.24 11.473±0.92 10.240±0.59 4.306±0.26 2.813±0.86 4.267±1.58 1.095±0.14 19.515±4.43 4.319±2.03 2.782±1.40
ENSMUST00000108714 N/A 3.235±0.00 N/A N/A N/A N/A N/A N/A 0.411±0.05 0.540±0.00 N/A N/A N/A
ENSMUST00000125840 N/A 4.939±1.59 N/A N/A 4.582±0.00 N/A N/A 1.791±0.36 N/A N/A N/A N/A N/A
ENSMUST00000128478 N/A N/A N/A 1.033±0.00 N/A N/A N/A N/A 0.968±0.12 0.436±0.10 2.787±0.00 1.341±0.08 N/A
ENSMUST00000152755 N/A N/A N/A 10.381±2.80 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000153441 N/A N/A N/A 17.577±0.00 N/A N/A N/A N/A N/A N/A 45.924±0.00 21.106±5.90 7.950±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004707 IEA MAP kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0005829 IDA cytosol
GO:0006468 IDA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0016605 ISS PML body
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0030154 IEA cell differentiation
GO:0034115 IEA negative regulation of heterotypic cell-cell adhesion
GO:0036003 IEA positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0043066 IDA negative regulation of apoptotic process
GO:0045765 IMP regulation of angiogenesis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0051019 IEA mitogen-activated protein kinase binding
GO:0051247 IEA positive regulation of protein metabolic process
GO:0051534 IMP negative regulation of NFAT protein import into nucleus
GO:0060761 IEA negative regulation of response to cytokine stimulus
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071363 IEA cellular response to growth factor stimulus
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:1902176 IEA negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:2000352 IEA negative regulation of endothelial cell apoptotic process
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023110 mapk7 mitogen-activated protein kinase 7 protein_coding Danio_rerio
ENSG00000166484 MAPK7 mitogen-activated protein kinase 7 protein_coding Homo_sapiens

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