C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ephrin B2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001300 Efnb2 10090 - 8:8617434-8660773 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001319 Efnb2-001 8617434-8660773 protein_coding
  ENSMUST00000152698 Efnb2-002 8620597-8639363 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001319ENSMUST00000152698
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001319 5.974±1.60 3.326±0.59 7.090±0.49 13.739±7.69 2.794±0.39 13.751±1.75 1.610±0.28 2.622±1.23 0.373±0.26 31.029±17.67 1.552±0.40 6.989±2.49 7.076±3.78 0.895±0.24
ENSMUST00000152698 11.618±0.00 N/A N/A N/A 3.489±1.26 N/A 5.541±0.88 9.111±2.97 0.797±0.15 N/A N/A 28.984±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Y9 CIL_0008Y9_0002 VISTA 8:8188054-8791339

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001945 IMP lymph vessel development
GO:0002042 ISS cell migration involved in sprouting angiogenesis
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005925 IEA focal adhesion
GO:0007155 ISS cell adhesion
GO:0007411 IBA axon guidance
GO:0009887 IMP organ morphogenesis
GO:0010839 IMP negative regulation of keratinocyte proliferation
GO:0016021 IEA integral component of membrane
GO:0016477 IBA cell migration
GO:0046875 IBA ephrin receptor binding
GO:0048013 ISS ephrin receptor signaling pathway
GO:0048514 IMP blood vessel morphogenesis
GO:0050920 ISS regulation of chemotaxis
GO:2000727 IMP positive regulation of cardiac muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003783 efnb2b ephrin B2b protein_coding Danio_rerio
ENSDARG00000020164 efnb2a ephrin B2a protein_coding Danio_rerio
ENSDARG00000074050 efnb2b ephrin B2b protein_coding Danio_rerio
ENSG00000125266 EFNB2 ephrin-B2 protein_coding Homo_sapiens

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