C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosine kinase, non-receptor, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001583 Tnk1 10090 - 11:69851005-69858730 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001626 Tnk1-001 69851005-69858730 protein_coding
  ENSMUST00000108626 Tnk1-003 69854480-69858730 protein_coding
  ENSMUST00000108628 Tnk1-002 69851219-69857125 protein_coding
  ENSMUST00000125571 Tnk1-005 69855581-69858708 protein_coding
  ENSMUST00000156507 Tnk1-004 69852075-69855602 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLungPlacentaTestisENSMUST00000001626ENSMUST00000108628
Transcript ID Bladder Brain Breast Colon Kidney Lung Placenta Testis
ENSMUST00000001626 7.849±0.39 0.538±0.00 5.147±0.57 10.830±4.52 3.398±0.35 6.124±0.22 2.415±0.36 0.691±0.19
ENSMUST00000108628 N/A N/A N/A 8.120±0.44 N/A N/A 1.219±0.00 0.377±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005524 IMP ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006468 IEA protein phosphorylation
GO:0016020 IEA membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030054 IEA cell junction
GO:0030308 IMP negative regulation of cell growth
GO:0046580 IMP negative regulation of Ras protein signal transduction
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069433 tnk1 tyrosine kinase, non-receptor, 1 protein_coding Danio_rerio
ENSG00000174292 TNK1 tyrosine kinase, non-receptor, 1 protein_coding Homo_sapiens

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