C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosine kinase, non-receptor, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174292 TNK1 9606 + 17:7380534-7389774 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000570896 TNK1-002 7380534-7389774 protein_coding
  ENST00000574794 TNK1-005 7381089-7383468 retained_intron
  ENST00000575268 TNK1-003 7381046-7383728 retained_intron
  ENST00000576136 TNK1-006 7384266-7386655 retained_intron
  ENST00000576207 TNK1-009 7381091-7383718 nonsense_mediated_decay
  ENST00000576716 TNK1-007 7387134-7388699 protein_coding
  ENST00000576812 TNK1-001 7380837-7389737 protein_coding
  ENST00000577009 TNK1-008 7384247-7386622 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungOvaryTestisENST00000570896ENST00000576812
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Ovary Testis
ENST00000570896 N/A 0.916±0.00 N/A 0.780±0.00 N/A 0.383±0.00 0.286±0.00 2.590±0.00 2.971±0.00
ENST00000576812 0.558±0.00 N/A 0.403±0.00 2.997±0.00 4.602±0.00 N/A 0.290±0.00 0.691±0.00 3.154±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SR CIL_0006SR_0002 CGP 17:7380534-7394843

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0004715 NAS non-membrane spanning protein tyrosine kinase activity
GO:0004871 TAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0006468 TAS:IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030054 IDA cell junction
GO:0030308 IEA negative regulation of cell growth
GO:0046580 IEA negative regulation of Ras protein signal transduction
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069433 tnk1 tyrosine kinase, non-receptor, 1 protein_coding Danio_rerio
ENSMUSG00000001583 Tnk1 tyrosine kinase, non-receptor, 1 protein_coding Mus_musculus

Loading