C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal transducer and activator of transcription 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002147 Stat6 10090 + 10:127642986-127660957 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000092074 Stat6-001 127642986-127660957 protein_coding
  ENSMUST00000120279 Stat6-002 127643002-127650780 protein_coding
  ENSMUST00000128072 Stat6-003 127653079-127655015 retained_intron
  ENSMUST00000145470 Stat6-005 127659400-127660187 retained_intron
  ENSMUST00000156231 Stat6-004 127656761-127657928 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000092074
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000092074 41.873±6.72 37.435±2.38 34.963±1.18 2.286±0.14 43.330±4.40 31.653±4.19 16.441±2.49 24.702±1.25 13.385±3.21 42.965±1.83 6.376±1.39 28.744±7.86 9.348±2.90

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0002296 IGI T-helper 1 cell lineage commitment
GO:0002829 IGI negative regulation of type 2 immune response
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007165 IMP signal transduction
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019903 IEA protein phosphatase binding
GO:0033598 IMP mammary gland epithelial cell proliferation
GO:0034097 IEA response to cytokine
GO:0035771 IMP interleukin-4-mediated signaling pathway
GO:0042127 IDA regulation of cell proliferation
GO:0042802 IEA identical protein binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045121 IEA membrane raft
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048295 IGI positive regulation of isotype switching to IgE isotypes
GO:0060443 IMP mammary gland morphogenesis
GO:0070301 IEA cellular response to hydrogen peroxide
GO:1902170 IEA cellular response to reactive nitrogen species

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015902 stat6 signal transducer and activator of transcription 6, interleukin-4 induced protein_coding Danio_rerio
ENSG00000166888 STAT6 signal transducer and activator of transcription 6, interleukin-4 induced protein_coding Homo_sapiens

Loading