C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E74-like factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003051 Elf3 10090 - 1:135253575-135258568 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003135 Elf3-001 135253575-135258568 protein_coding
  ENSMUST00000185752 Elf3-002 135253579-135258438 protein_coding
  ENSMUST00000188895 Elf3-003 135256657-135257649 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastColonKidneyLungOvaryPlacentaTestisENSMUST00000003135ENSMUST00000185752
Transcript ID Adipose Bladder Breast Colon Kidney Lung Ovary Placenta Testis
ENSMUST00000003135 5.250±0.57 10.171±1.15 3.049±0.10 83.231±17.93 3.577±0.95 4.605±0.41 6.118±0.88 12.902±8.62 N/A
ENSMUST00000185752 11.698±0.00 19.662±1.60 5.554±0.39 193.798±7.73 7.287±0.47 7.004±0.50 13.580±4.01 25.662±11.14 1.029±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001824 IMP blastocyst development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003713 ISS transcription coactivator activity
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0006954 ISS inflammatory response
GO:0009653 IMP anatomical structure morphogenesis
GO:0030154 IBA cell differentiation
GO:0030198 IMP extracellular matrix organization
GO:0030855 ISS epithelial cell differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0060056 IDA mammary gland involution

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077982 elf3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) protein_coding Danio_rerio
ENSG00000163435 ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) protein_coding Homo_sapiens

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