C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CREB regulated transcription coactivator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003575 Crtc1 10090 - 8:70382355-70439579 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076615 Crtc1-001 70382355-70439579 protein_coding
  ENSMUST00000125273 Crtc1-002 70397755-70402798 retained_intron
  ENSMUST00000125613 Crtc1-004 70404849-70439575 retained_intron
  ENSMUST00000142769 Crtc1-005 70382355-70439579 retained_intron
  ENSMUST00000153632 Crtc1-003 70406127-70431285 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076615ENSMUST00000125613ENSMUST00000142769
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076615 4.615±1.53 14.993±1.65 3.377±0.20 19.428±6.00 7.501±3.61 6.640±0.45 3.367±0.83 4.849±0.48 1.897±0.62 5.649±0.36 2.282±0.20 15.045±7.30 2.091±0.76 2.366±1.13
ENSMUST00000125613 N/A N/A N/A N/A N/A N/A N/A N/A 1.957±0.06 N/A N/A N/A N/A N/A
ENSMUST00000142769 0.708±0.38 1.343±0.09 0.361±0.00 1.148±0.20 1.001±0.17 0.770±0.13 0.446±0.11 0.455±0.08 0.217±0.10 0.771±0.09 0.214±0.00 2.306±0.25 0.225±0.02 0.366±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0007613 IMP memory
GO:0008140 ISS cAMP response element binding protein binding
GO:0032793 IMP positive regulation of CREB transcription factor activity
GO:0043153 IMP entrainment of circadian clock by photoperiod
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0051289 IEA protein homotetramerization
GO:0060081 IDA membrane hyperpolarization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076068 crtc1a CREB regulated transcription coactivator 1a protein_coding Danio_rerio
ENSDARG00000076076 crtc1b CREB regulated transcription coactivator 1b protein_coding Danio_rerio
ENSG00000105662 CRTC1 CREB regulated transcription coactivator 1 protein_coding Homo_sapiens

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