C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CREB regulated transcription coactivator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105662 CRTC1 9606 + 19:18683677-18782333 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000321949 CRTC1-002 18683677-18777952 protein_coding
  ENST00000338797 CRTC1-001 18683678-18782333 protein_coding
  ENST00000594658 CRTC1-003 18735609-18777952 protein_coding
  ENST00000601916 CRTC1-004 18742910-18777938 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000321949ENST00000338797ENST00000594658ENST00000601916
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000321949 8.442±0.00 4.438±0.00 1.505±0.00 5.322±3.08 1.709±1.09 2.003±1.33 1.414±1.11 2.524±1.73 N/A 1.212±0.67 6.754±0.00 6.717±6.87 3.597±2.69 6.824±4.96
ENST00000338797 N/A N/A N/A 2.087±1.57 N/A 1.400±0.00 0.282±0.00 0.080±0.00 0.028±0.00 0.238±0.00 1.272±0.00 1.438±1.35 N/A N/A
ENST00000594658 N/A N/A N/A N/A N/A N/A N/A N/A 0.759±0.00 0.635±0.00 N/A 9.405±0.00 6.114±0.85 8.675±0.00
ENST00000601916 N/A N/A N/A N/A 1.997±0.00 1.583±0.00 1.209±0.00 N/A 0.567±0.00 2.298±0.00 N/A 1.571±0.00 N/A 3.433±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004NM CIL_0004NM_0002 CGP 19:18636965-18782333
CIL_0004NL CIL_0004NL_0002 CGP 19:18683677-18791314

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0007613 IEA memory
GO:0008140 IDA cAMP response element binding protein binding
GO:0016032 IEA viral process
GO:0032793 ISS positive regulation of CREB transcription factor activity
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051289 IEA protein homotetramerization
GO:0060081 IEA membrane hyperpolarization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076068 crtc1a CREB regulated transcription coactivator 1a protein_coding Danio_rerio
ENSDARG00000076076 crtc1b CREB regulated transcription coactivator 1b protein_coding Danio_rerio
ENSMUSG00000003575 Crtc1 CREB regulated transcription coactivator 1 protein_coding Mus_musculus

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