C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004054 Map3k11 10090 + 19:5689131-5702862 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004156 Map3k11-201 5689131-5702862 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004156
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004156 20.023±1.76 22.539±11.65 8.867±0.24 8.739±3.60 22.167±13.14 36.866±7.72 5.885±1.42 19.751±6.08 12.004±3.25 46.019±4.94 4.093±0.52 24.066±7.43 14.668±8.31 7.112±3.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W1 CIL_0008W1_0002 VISTA 19:5510095-6112698

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004706 IEA JUN kinase kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005813 IEA centrosome
GO:0005874 IEA microtubule
GO:0007017 IEA microtubule-based process
GO:0007254 IEA JNK cascade
GO:0007256 IEA activation of JNKK activity
GO:0007257 IEA activation of JUN kinase activity
GO:0008219 IEA cell death
GO:0008283 IEA cell proliferation
GO:0016020 IEA membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0031435 IEA mitogen-activated protein kinase kinase kinase binding
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043065 IEA positive regulation of apoptotic process
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0046330 IEA positive regulation of JNK cascade
GO:0046777 IEA protein autophosphorylation
GO:0048365 IEA Rac GTPase binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091521 MAP3K11 mitogen-activated protein kinase kinase kinase 11 protein_coding Danio_rerio
ENSG00000173327 MAP3K11 mitogen-activated protein kinase kinase kinase 11 protein_coding Homo_sapiens

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