C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU domain, class 1, transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004842 Pou1f1 10090 + 16:65520511-65535005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004964 Pou1f1-201 65520512-65535005 protein_coding
  ENSMUST00000175882 Pou1f1-003 65520512-65525543 retained_intron
  ENSMUST00000176038 Pou1f1-002 65520548-65534120 protein_coding
  ENSMUST00000176330 Pou1f1-001 65520511-65534297 protein_coding
  ENSMUST00000184525 Pou1f1-004 65523277-65533981 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004964ENSMUST00000176038ENSMUST00000176330
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004964 0.314±0.12 0.280±0.20 0.009±0.00 0.282±0.26 0.314±0.12 0.122±0.07 0.210±0.06 0.118±0.03 0.144±0.11 0.095±0.07 N/A 0.670±0.45 0.010±0.00 0.158±0.06
ENSMUST00000176038 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.021±0.00 N/A N/A N/A
ENSMUST00000176330 N/A 0.164±0.03 0.110±0.10 0.183±0.07 0.209±0.00 N/A N/A N/A 0.054±0.04 0.038±0.01 N/A 0.137±0.09 0.053±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001105 IEA RNA polymerase II transcription coactivator activity
GO:0001708 IDA cell fate specification
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IC transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008134 IPI transcription factor binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0008340 IMP determination of adult lifespan
GO:0021983 IMP pituitary gland development
GO:0021984 IEA adenohypophysis development
GO:0030183 IMP B cell differentiation
GO:0032962 IMP positive regulation of inositol trisphosphate biosynthetic process
GO:0040018 IMP positive regulation of multicellular organism growth
GO:0043565 IDA sequence-specific DNA binding
GO:0043567 IMP regulation of insulin-like growth factor receptor signaling pathway
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0051169 IEA nuclear transport
GO:0060126 IMP somatotropin secreting cell differentiation
GO:0060133 IMP somatotropin secreting cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058924 pou1f1 POU domain, class 1, transcription factor 1 protein_coding Danio_rerio
ENSG00000064835 POU1F1 POU class 1 homeobox 1 protein_coding Homo_sapiens

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