C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU class 1 homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000064835 POU1F1 9606 - 3:87259404-87276587 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344265 POU1F1-002 87259741-87276504 protein_coding
  ENST00000350375 POU1F1-001 87259404-87276587 protein_coding
  ENST00000560656 POU1F1-003 87259897-87276462 protein_coding
  ENST00000561167 POU1F1-004 87259895-87276462 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartKidneyLungOvaryPlacentaTestisENST00000350375ENST00000560656ENST00000561167
Transcript ID Adrenal Brain Breast Heart Kidney Lung Ovary Placenta Testis
ENST00000350375 0.055±0.00 0.133±0.00 0.045±0.00 0.058±0.00 0.053±0.00 0.114±0.00 0.024±0.01 0.055±0.00 0.019±0.00
ENST00000560656 N/A N/A N/A N/A N/A N/A N/A N/A 0.161±0.00
ENST00000561167 N/A N/A N/A N/A N/A N/A N/A N/A 0.127±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00022L CIL_00022L_0002 CGP 3:87259404-87993835

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0001708 IEA cell fate specification
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003714 IEA transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0008134 IEA transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0008340 IEA determination of adult lifespan
GO:0021983 IEA pituitary gland development
GO:0021984 IEA adenohypophysis development
GO:0030183 IEA B cell differentiation
GO:0032962 IEA positive regulation of inositol trisphosphate biosynthetic process
GO:0040018 IEA positive regulation of multicellular organism growth
GO:0043565 IEA sequence-specific DNA binding
GO:0043567 IEA regulation of insulin-like growth factor receptor signaling pathway
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051169 IEA nuclear transport
GO:0060126 IEA somatotropin secreting cell differentiation
GO:0060133 IEA somatotropin secreting cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058924 pou1f1 POU domain, class 1, transcription factor 1 protein_coding Danio_rerio
ENSMUSG00000004842 Pou1f1 POU domain, class 1, transcription factor 1 protein_coding Mus_musculus

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