C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, cAMP dependent, catalytic, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005034 Prkacb 10090 - 3:146729579-146812960 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005164 Prkacb-002 146729867-146781416 protein_coding
  ENSMUST00000102515 Prkacb-001 146729579-146812960 protein_coding
  ENSMUST00000106137 Prkacb-004 146729865-146770261 protein_coding
  ENSMUST00000106138 Prkacb-003 146729865-146770781 protein_coding
  ENSMUST00000144369 Prkacb-005 146732328-146745627 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005164ENSMUST00000102515ENSMUST00000106137ENSMUST00000106138ENSMUST00000144369
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005164 4.868±1.33 N/A N/A N/A 9.068±1.63 16.493±1.60 3.456±0.30 3.847±0.72 1.602±0.49 5.334±0.70 N/A 5.881±0.00 N/A 0.582±0.19
ENSMUST00000102515 12.381±4.94 39.920±4.02 44.920±2.46 32.276±3.99 8.249±4.05 10.691±0.84 7.879±0.91 11.336±1.93 7.657±1.64 15.958±1.88 10.924±0.67 23.198±5.11 8.301±1.05 1.488±0.60
ENSMUST00000106137 N/A N/A N/A 21.766±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000106138 N/A N/A N/A 9.683±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.012±0.16
ENSMUST00000144369 N/A N/A N/A N/A 16.228±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0001843 IGI neural tube closure
GO:0004691 IDA cAMP-dependent protein kinase activity
GO:0005515 IEA protein binding
GO:0005524 IDA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005813 IEA centrosome
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005952 TAS cAMP-dependent protein kinase complex
GO:0006468 IDA protein phosphorylation
GO:0007188 TAS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0031625 IEA ubiquitin protein ligase binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051447 IEA negative regulation of meiotic cell cycle
GO:0070062 IEA extracellular vesicular exosome
GO:0070613 IGI regulation of protein processing
GO:0097338 IEA response to clozapine
GO:0097546 IDA ciliary base
GO:1901621 IGI negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059125 prkacbb protein kinase, cAMP-dependent, catalytic, beta b protein_coding Danio_rerio
ENSDARG00000087866 prkacbb protein kinase, cAMP-dependent, catalytic, beta b protein_coding Danio_rerio
ENSG00000142875 PRKACB protein kinase, cAMP-dependent, catalytic, beta protein_coding Homo_sapiens

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