C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosinase-related protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005994 Tyrp1 10090 + 4:80834123-80851719 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006151 Tyrp1-201 80834230-80851718 protein_coding
  ENSMUST00000102831 Tyrp1-001 80834307-80851719 protein_coding
  ENSMUST00000133655 Tyrp1-003 80834123-80837684 protein_coding
  ENSMUST00000133932 Tyrp1-002 80846588-80851000 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000102831ENSMUST00000133655ENSMUST00000133932
Transcript ID Adipose Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000102831 0.012±0.00 0.009±0.00 0.071±0.04 0.023±0.01 0.033±0.02 0.022±0.00 0.003±0.00 0.024±0.00 0.053±0.06 0.011±0.00 0.004±0.00
ENSMUST00000133655 N/A N/A 0.123±0.00 N/A 0.015±0.00 0.011±0.00 N/A N/A N/A N/A N/A
ENSMUST00000133932 N/A 0.036±0.00 N/A 0.095±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005UW CIL_0005UW_0003 CGP 4:75941238-80851719
CIL_00012W CIL_00012W_0002 CGP 4:80834123-80955628

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005507 IEA copper ion binding
GO:0005515 IPI protein binding
GO:0006582 IMP melanin metabolic process
GO:0006583 TAS melanin biosynthetic process from tyrosine
GO:0010008 IEA endosome membrane
GO:0016021 IEA integral component of membrane
GO:0016716 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
GO:0030318 IMP melanocyte differentiation
GO:0030669 IEA clathrin-coated endocytic vesicle membrane
GO:0032438 IMP melanosome organization
GO:0033162 IEA:IDA melanosome membrane
GO:0042438 IEA melanin biosynthetic process
GO:0042470 IDA melanosome
GO:0042803 IDA protein homodimerization activity
GO:0043438 IMP acetoacetic acid metabolic process
GO:0043473 IMP pigmentation
GO:0046982 IDA protein heterodimerization activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029204 tyrp1a tyrosinase-related protein 1a protein_coding Danio_rerio
ENSDARG00000056151 tyrp1b tyrosinase-related protein 1b protein_coding Danio_rerio
ENSG00000107165 TYRP1 tyrosinase-related protein 1 protein_coding Homo_sapiens

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