C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inositol polyphosphate 5-phosphatase K
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006127 Inpp5k 10090 + 11:75630988-75648871 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006286 Inpp5k-001 75630988-75648871 protein_coding
  ENSMUST00000129298 Inpp5k-004 75631037-75635268 retained_intron
  ENSMUST00000130318 Inpp5k-005 75639137-75647276 retained_intron
  ENSMUST00000136605 Inpp5k-007 75631029-75648863 retained_intron
  ENSMUST00000139856 Inpp5k-002 75646846-75647864 protein_coding
  ENSMUST00000149134 Inpp5k-006 75646786-75647731 processed_transcript
  ENSMUST00000150857 Inpp5k-003 75631055-75648865 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006286ENSMUST00000130318ENSMUST00000136605ENSMUST00000149134ENSMUST00000150857
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006286 21.403±2.19 12.947±1.27 19.573±1.54 14.012±5.83 20.166±4.89 15.199±1.44 12.526±0.94 21.761±1.42 7.075±1.99 43.027±3.48 12.243±0.46 20.939±7.01 8.999±5.16 40.404±19.85
ENSMUST00000130318 N/A 15.332±2.61 N/A N/A N/A 11.867±0.00 N/A N/A N/A N/A N/A 14.492±2.49 N/A N/A
ENSMUST00000136605 4.467±0.16 4.921±0.73 3.872±0.24 2.640±0.77 5.919±1.02 5.413±0.95 2.016±0.46 3.833±0.91 1.497±0.40 9.828±0.21 N/A 4.784±0.89 2.835±2.72 N/A
ENSMUST00000149134 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.370±0.00 N/A N/A
ENSMUST00000150857 N/A 5.924±1.00 N/A N/A 14.076±7.08 N/A N/A N/A N/A N/A N/A 8.990±0.00 N/A 3.384±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001726 ISS ruffle
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0004445 IEA inositol-polyphosphate 5-phosphatase activity
GO:0005000 IDA vasopressin receptor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005802 ISS trans-Golgi network
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0005979 IMP regulation of glycogen biosynthetic process
GO:0006469 ISS negative regulation of protein kinase activity
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0010801 ISS negative regulation of peptidyl-threonine phosphorylation
GO:0010829 ISS negative regulation of glucose transport
GO:0016020 ISS membrane
GO:0016311 IDA dephosphorylation
GO:0016312 ISS inositol bisphosphate phosphatase activity
GO:0032587 ISS ruffle membrane
GO:0032868 IMP response to insulin
GO:0032869 ISS cellular response to insulin stimulus
GO:0032870 IDA cellular response to hormone stimulus
GO:0033137 IMP negative regulation of peptidyl-serine phosphorylation
GO:0034485 IDA phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0034594 ISS phosphatidylinositol trisphosphate phosphatase activity
GO:0034595 ISS phosphatidylinositol phosphate 5-phosphatase activity
GO:0035305 IMP negative regulation of dephosphorylation
GO:0035810 IDA positive regulation of urine volume
GO:0042593 IMP glucose homeostasis
GO:0043005 ISS neuron projection
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0043922 ISS negative regulation by host of viral transcription
GO:0045719 IMP negative regulation of glycogen biosynthetic process
GO:0045869 ISS negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046030 ISS inositol trisphosphate phosphatase activity
GO:0046627 IMP negative regulation of insulin receptor signaling pathway
GO:0046855 ISA inositol phosphate dephosphorylation
GO:0046856 ISS phosphatidylinositol dephosphorylation
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051497 ISS negative regulation of stress fiber assembly
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0051926 ISS negative regulation of calcium ion transport
GO:0052658 IEA inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0052659 IEA inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
GO:0071320 IDA cellular response to cAMP
GO:0071356 ISS cellular response to tumor necrosis factor
GO:0071364 ISS cellular response to epidermal growth factor stimulus
GO:0072661 IDA protein targeting to plasma membrane
GO:0090315 ISS negative regulation of protein targeting to membrane
GO:0097178 ISS ruffle assembly
GO:2000466 IMP negative regulation of glycogen (starch) synthase activity
GO:2001153 IDA positive regulation of renal water transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076338 INPP5K (1 of 2) inositol polyphosphate-5-phosphatase K protein_coding Danio_rerio
ENSDARG00000078618 inpp5k inositol polyphosphate-5-phosphatase K protein_coding Danio_rerio
ENSG00000132376 INPP5K inositol polyphosphate-5-phosphatase K protein_coding Homo_sapiens

Loading