C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inositol polyphosphate 5-phosphatase K
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000006286 Inpp5k-001 ENSMUSG00000006127 10090 + 11:75630988-75648871 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006286
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006286 21.403±2.19 12.947±1.27 19.573±1.54 14.012±5.83 20.166±4.89 15.199±1.44 12.526±0.94 21.761±1.42 7.075±1.99 43.027±3.48 12.243±0.46 20.939±7.01 8.999±5.16 40.404±19.85

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001726 ISS ruffle
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0004445 IEA inositol-polyphosphate 5-phosphatase activity
GO:0005000 IDA vasopressin receptor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005802 ISS trans-Golgi network
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0005979 IMP regulation of glycogen biosynthetic process
GO:0006469 ISS negative regulation of protein kinase activity
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0010801 ISS negative regulation of peptidyl-threonine phosphorylation
GO:0010829 ISS negative regulation of glucose transport
GO:0016020 ISS membrane
GO:0016311 IDA dephosphorylation
GO:0016312 ISS inositol bisphosphate phosphatase activity
GO:0032587 ISS ruffle membrane
GO:0032868 IMP response to insulin
GO:0032869 ISS cellular response to insulin stimulus
GO:0032870 IDA cellular response to hormone stimulus
GO:0033137 IMP negative regulation of peptidyl-serine phosphorylation
GO:0034485 IDA phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0034594 ISS phosphatidylinositol trisphosphate phosphatase activity
GO:0034595 ISS phosphatidylinositol phosphate 5-phosphatase activity
GO:0035305 IMP negative regulation of dephosphorylation
GO:0035810 IDA positive regulation of urine volume
GO:0042593 IMP glucose homeostasis
GO:0043005 ISS neuron projection
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0043922 ISS negative regulation by host of viral transcription
GO:0045719 IMP negative regulation of glycogen biosynthetic process
GO:0045869 ISS negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046030 ISS inositol trisphosphate phosphatase activity
GO:0046627 IMP negative regulation of insulin receptor signaling pathway
GO:0046855 ISA inositol phosphate dephosphorylation
GO:0046856 ISS phosphatidylinositol dephosphorylation
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051497 ISS negative regulation of stress fiber assembly
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0051926 ISS negative regulation of calcium ion transport
GO:0052658 IEA inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0052659 IEA inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
GO:0071320 IDA cellular response to cAMP
GO:0071356 ISS cellular response to tumor necrosis factor
GO:0071364 ISS cellular response to epidermal growth factor stimulus
GO:0072661 IDA protein targeting to plasma membrane
GO:0090315 ISS negative regulation of protein targeting to membrane
GO:0097178 ISS ruffle assembly
GO:2000466 IMP negative regulation of glycogen (starch) synthase activity
GO:2001153 IDA positive regulation of renal water transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000320345 INPP5K-004 protein_coding Homo_sapiens 0 1131
ENST00000350761 INPP5K-016 nonsense_mediated_decay Homo_sapiens 0 939
ENST00000406424 INPP5K-003 protein_coding Homo_sapiens 0 1131
ENST00000421807 INPP5K-001 protein_coding Homo_sapiens 0 1149
ENST00000449479 INPP5K-007 protein_coding Homo_sapiens 0 590
ENST00000477115 INPP5K-010 retained_intron Homo_sapiens 0 191
ENST00000481867 INPP5K-009 retained_intron Homo_sapiens 0 272
ENST00000495339 INPP5K-011 retained_intron Homo_sapiens 5e-32 141

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