C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myeloproliferative leukemia virus oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006389 Mpl 10090 - 4:118442415-118457513 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006556 Mpl-003 118443272-118457457 protein_coding
  ENSMUST00000102671 Mpl-001 118442415-118457513 protein_coding
  ENSMUST00000106375 Mpl-002 118443429-118457450 protein_coding
  ENSMUST00000168404 Mpl-201 118442417-118457495 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006556ENSMUST00000102671ENSMUST00000106375ENSMUST00000168404
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006556 0.027±0.00 N/A N/A N/A 0.044±0.00 N/A 0.163±0.00 N/A 0.027±0.00 N/A N/A N/A 0.455±0.00 N/A
ENSMUST00000102671 0.022±0.00 0.010±0.00 0.016±0.00 0.045±0.02 0.076±0.00 0.018±0.01 0.116±0.00 0.016±0.01 1.975±1.42 0.555±0.08 0.012±0.00 0.024±0.01 0.289±0.10 0.003±0.00
ENSMUST00000106375 N/A N/A N/A N/A 0.017±0.00 N/A N/A 0.022±0.01 0.018±0.00 N/A 0.049±0.00 0.049±0.00 N/A 0.015±0.00
ENSMUST00000168404 0.021±0.00 0.010±0.00 0.002±0.00 0.019±0.01 0.046±0.00 0.011±0.01 0.057±0.02 0.015±0.01 1.396±1.00 0.119±0.00 0.012±0.00 0.025±0.01 0.100±0.06 0.003±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003N3 CIL_0003N3_0002 CGP 4:118442415-118490061

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004896 IEA cytokine receptor activity
GO:0005886 IEA plasma membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0032642 IMP regulation of chemokine production
GO:0048872 IMP homeostasis of number of cells

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039222 mpl myeloproliferative leukemia virus oncogene protein_coding Danio_rerio
ENSG00000117400 MPL MPL proto-oncogene, thrombopoietin receptor protein_coding Homo_sapiens

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