C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006403 Adamts4 10090 + 1:171250421-171260637 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006570 Adamts4-201 171250423-171260636 protein_coding
  ENSMUST00000111314 Adamts4-002 171252116-171260637 protein_coding
  ENSMUST00000111315 Adamts4-001 171250421-171260637 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006570ENSMUST00000111314ENSMUST00000111315
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006570 3.276±2.63 0.610±0.19 0.062±0.00 0.935±0.21 2.432±1.03 1.266±0.18 0.203±0.03 0.279±0.09 0.117±0.09 0.249±0.06 0.051±0.03 9.624±2.81 2.705±0.84 0.098±0.02
ENSMUST00000111314 0.588±0.41 N/A 0.043±0.00 0.305±0.00 0.917±0.49 0.445±0.00 0.148±0.00 0.176±0.03 0.107±0.03 0.121±0.03 0.028±0.01 2.125±0.48 2.620±0.83 0.235±0.13
ENSMUST00000111315 1.420±1.34 0.579±0.18 0.060±0.00 0.287±0.00 1.961±0.69 1.148±0.14 0.211±0.08 0.264±0.08 0.126±0.14 0.241±0.06 0.049±0.03 7.512±3.68 2.447±1.53 0.103±0.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0004222 IDA metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IEA extracellular space
GO:0006508 IDA proteolysis
GO:0008237 IDA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0031012 IDA extracellular matrix
GO:0042742 IGI defense response to bacterium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000158859 ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 protein_coding Homo_sapiens

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