C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase with thrombospondin type 1 motif, 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158859 ADAMTS4 9606 - 1:161184308-161199056 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367995 ADAMTS4-002 161195979-161199053 protein_coding
  ENST00000367996 ADAMTS4-001 161184308-161199056 protein_coding
  ENST00000478394 ADAMTS4-003 161194162-161195751 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367995ENST00000367996
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367995 53.921±0.00 N/A 0.437±0.00 9.536±7.25 3.330±0.98 15.567±0.00 2.037±1.93 N/A 4.565±0.00 62.579±0.00 1.435±0.76 1.113±0.00 0.972±0.30 1.438±0.00
ENST00000367996 28.086±0.00 2.484±0.00 0.139±0.00 4.433±3.85 0.946±0.66 3.933±3.76 2.374±0.00 0.573±0.39 1.350±0.01 21.425±21.30 1.124±0.84 6.956±5.16 0.589±0.18 0.401±0.13

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0002020 IPI protease binding
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0006508 IEA proteolysis
GO:0008233 TAS peptidase activity
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0031012 IDA:IEA extracellular matrix
GO:0042742 IEA defense response to bacterium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000006403 Adamts4 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 protein_coding Mus_musculus

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