C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2, regulatory subunit A, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000007564 Ppp2r1a 10090 + 17:20945311-20965916 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000007708 Ppp2r1a-001 20945311-20965916 protein_coding
  ENSMUST00000136975 Ppp2r1a-003 20958741-20960598 retained_intron
  ENSMUST00000138971 Ppp2r1a-004 20960490-20961266 retained_intron
  ENSMUST00000139293 Ppp2r1a-005 20958989-20961942 retained_intron
  ENSMUST00000147983 Ppp2r1a-002 20956778-20959509 protein_coding
  ENSMUST00000173359 Ppp2r1a-006 20956577-20958837 retained_intron
  ENSMUST00000173658 Ppp2r1a-007 20945487-20958784 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000007708ENSMUST00000139293ENSMUST00000173658
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000007708 111.227±1.27 119.833±12.02 82.686±0.60 133.828±42.81 79.336±5.02 102.720±3.93 78.510±4.97 78.025±4.95 32.581±6.40 81.263±1.91 39.027±1.65 87.957±23.40 65.950±28.04 11.108±5.17
ENSMUST00000139293 N/A N/A N/A 117.048±0.00 N/A N/A N/A N/A N/A N/A N/A 42.883±0.00 65.728±19.85 5.480±0.00
ENSMUST00000173658 N/A N/A N/A 61.580±0.00 N/A N/A N/A N/A N/A N/A N/A 23.549±0.00 N/A 2.709±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000159 IDA protein phosphatase type 2A complex
GO:0000775 ISS chromosome, centromeric region
GO:0003823 IEA antigen binding
GO:0004722 IDA protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0007059 ISS chromosome segregation
GO:0046982 IEA protein heterodimerization activity
GO:0070062 IEA extracellular vesicular exosome
GO:0070262 IDA peptidyl-serine dephosphorylation
GO:2001241 IMP positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000105568 PPP2R1A protein phosphatase 2, regulatory subunit A, alpha protein_coding Homo_sapiens

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