C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000007653 Gabrb2 10090 + 11:42419757-42629028 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000007797 Gabrb2-001 42419757-42629028 protein_coding
  ENSMUST00000136050 Gabrb2-004 42421279-42487545 processed_transcript
  ENSMUST00000140463 Gabrb2-003 42419764-42422638 processed_transcript
  ENSMUST00000143626 Gabrb2-002 42421310-42531622 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000007797ENSMUST00000136050ENSMUST00000140463ENSMUST00000143626
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000007797 0.136±0.10 4.835±0.09 0.041±0.01 N/A 0.039±0.00 0.010±0.00 0.007±0.00 0.026±0.00 0.013±0.00 0.333±0.14 0.008±0.00 0.021±0.01
ENSMUST00000136050 0.308±0.08 N/A 0.126±0.03 0.205±0.00 0.066±0.00 N/A 0.037±0.00 N/A 0.032±0.00 1.086±0.52 0.025±0.00 N/A
ENSMUST00000140463 N/A N/A N/A N/A N/A N/A 0.025±0.00 N/A N/A N/A 0.016±0.00 0.090±0.00
ENSMUST00000143626 0.024±0.00 N/A 0.018±0.00 N/A 0.017±0.00 N/A 0.004±0.00 N/A N/A 0.356±0.24 0.003±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004890 ISS GABA-A receptor activity
GO:0005237 IEA inhibitory extracellular ligand-gated ion channel activity
GO:0005254 ISS chloride channel activity
GO:0005515 IPI protein binding
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007165 IEA signal transduction
GO:0007605 IMP sensory perception of sound
GO:0030054 IEA cell junction
GO:0034220 IEA ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0043523 IMP regulation of neuron apoptotic process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045211 IEA postsynaptic membrane
GO:0048666 IMP neuron development
GO:0051932 IEA synaptic transmission, GABAergic
GO:0060119 IMP inner ear receptor cell development
GO:0060384 IMP innervation
GO:0070062 IEA extracellular vesicular exosome
GO:0071420 ISS cellular response to histamine
GO:0090102 IMP cochlea development
GO:1901215 IMP negative regulation of neuron death
GO:1902476 ISS chloride transmembrane transport
GO:1902711 ISS GABA-A receptor complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018935 GABRB2 (1 of 2) gamma-aminobutyric acid (GABA) A receptor, beta 2 protein_coding Danio_rerio
ENSDARG00000079586 gabrb2 gamma-aminobutyric acid (GABA) A receptor, beta 2 protein_coding Danio_rerio
ENSG00000145864 GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 protein_coding Homo_sapiens

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