C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytokine receptor-like factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000007888 Crlf1 10090 + 8:70493158-70504081 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000008032 Crlf1-001 70493158-70504081 protein_coding
  ENSMUST00000127983 Crlf1-005 70501133-70504030 protein_coding
  ENSMUST00000132648 Crlf1-004 70493361-70500930 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000008032ENSMUST00000127983ENSMUST00000132648
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000008032 0.301±0.16 0.098±0.03 0.128±0.05 0.351±0.08 0.430±0.12 0.623±0.35 0.228±0.09 0.473±0.13 0.144±0.21 8.044±2.35 1.274±0.48 2.257±1.17 1.164±0.58 4.783±2.76
ENSMUST00000127983 1.438±0.60 0.499±0.19 N/A 1.030±0.00 1.837±0.44 1.843±0.57 0.350±0.03 0.554±0.10 0.464±0.28 N/A N/A 2.187±0.82 1.598±1.00 51.733±20.95
ENSMUST00000132648 N/A N/A N/A N/A 0.607±0.00 N/A N/A N/A N/A N/A N/A 1.152±0.00 3.844±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006BB CIL_0006BB_0002 CGP 8:70483876-70504081
CIL_0004NN CIL_0004NN_0003 CGP 8:70493158-70506752

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001657 IEP ureteric bud development
GO:0005125 IEA cytokine activity
GO:0005127 TAS ciliary neurotrophic factor receptor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0019955 IEA cytokine binding
GO:0042517 IEA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0046982 TAS protein heterodimerization activity
GO:0097058 IEA CRLF-CLCF1 complex
GO:2000672 IMP negative regulation of motor neuron apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006368 crlf1b cytokine receptor-like factor 1b protein_coding Danio_rerio
ENSDARG00000024365 crlf1a cytokine receptor-like factor 1a protein_coding Danio_rerio
ENSG00000006016 CRLF1 cytokine receptor-like factor 1 protein_coding Homo_sapiens

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