C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mutS homolog 3 (E. coli)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014850 Msh3 10090 - 13:92211872-92355003 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022220 Msh3-002 92211886-92355003 protein_coding
  ENSMUST00000185852 Msh3-004 92211872-92354995 protein_coding
  ENSMUST00000186392 Msh3-011 92211886-92250073 retained_intron
  ENSMUST00000186878 Msh3-007 92345869-92354953 retained_intron
  ENSMUST00000187424 Msh3-012 92351127-92354985 protein_coding
  ENSMUST00000187831 Msh3-008 92340672-92354515 processed_transcript
  ENSMUST00000187874 Msh3-015 92249854-92354985 nonsense_mediated_decay
  ENSMUST00000189376 Msh3-013 92312652-92345378 retained_intron
  ENSMUST00000190393 Msh3-006 92346520-92354985 nonsense_mediated_decay
  ENSMUST00000190462 Msh3-009 92307497-92309457 retained_intron
  ENSMUST00000190761 Msh3-014 92212257-92235599 protein_coding
  ENSMUST00000191242 Msh3-005 92211880-92241130 processed_transcript
  ENSMUST00000191304 Msh3-010 92211881-92266072 retained_intron
  ENSMUST00000191509 Msh3-003 92309180-92354996 nonsense_mediated_decay
  ENSMUST00000191550 Msh3-001 92211882-92354999 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLungMuscleOvaryPlacentaTestisENSMUST00000022220ENSMUST00000185852ENSMUST00000186392ENSMUST00000191242ENSMUST00000191304ENSMUST00000191509ENSMUST00000191550
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENSMUST00000022220 0.730±0.06 N/A 1.214±0.14 2.219±0.41 0.658±0.26 1.073±0.32 0.499±0.24 0.600±0.00 1.111±0.33 1.977±0.76 1.448±0.73 1.452±0.15
ENSMUST00000185852 0.930±0.16 0.891±0.04 N/A 1.788±0.00 1.120±0.00 0.546±0.13 0.370±0.00 0.654±0.00 1.256±0.48 1.824±0.78 N/A 1.170±0.50
ENSMUST00000186392 N/A N/A N/A N/A N/A N/A N/A 1.203±0.00 N/A N/A N/A N/A
ENSMUST00000191242 1.170±0.00 N/A N/A N/A N/A N/A N/A N/A 1.693±0.22 N/A 2.032±0.00 2.440±0.20
ENSMUST00000191304 N/A N/A 2.042±0.46 4.101±0.32 N/A 0.996±0.00 0.990±0.33 N/A 1.244±0.14 5.976±0.00 4.681±0.11 6.887±0.00
ENSMUST00000191509 0.504±0.12 0.911±0.11 N/A N/A 0.497±0.07 0.450±0.05 N/A 0.320±0.00 N/A 0.824±0.28 N/A N/A
ENSMUST00000191550 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.118±0.35 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000228 IBA nuclear chromosome
GO:0000403 IBA Y-form DNA binding
GO:0000404 IBA heteroduplex DNA loop binding
GO:0000406 IBA double-strand/single-strand DNA junction binding
GO:0000710 IBA meiotic mismatch repair
GO:0003677 IGI DNA binding
GO:0003684 IGI damaged DNA binding
GO:0003697 IEA single-stranded DNA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0006200 IBA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006298 IGI mismatch repair
GO:0007131 IBA reciprocal meiotic recombination
GO:0008094 IBA DNA-dependent ATPase activity
GO:0016020 IEA membrane
GO:0016447 IMP somatic recombination of immunoglobulin gene segments
GO:0019237 IDA centromeric DNA binding
GO:0019899 IEA enzyme binding
GO:0032139 IEA dinucleotide insertion or deletion binding
GO:0032142 IEA single guanine insertion binding
GO:0032181 IEA dinucleotide repeat insertion binding
GO:0032302 IBA MutSbeta complex
GO:0032357 IEA oxidized purine DNA binding
GO:0043570 IBA maintenance of DNA repeat elements
GO:0045910 IEA negative regulation of DNA recombination
GO:0051096 IEA positive regulation of helicase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063276 msh3 mutS homolog 3 (E. coli) protein_coding Danio_rerio
ENSDARG00000086810 msh3 mutS homolog 3 (E. coli) protein_coding Danio_rerio
ENSG00000113318 MSH3 mutS homolog 3 protein_coding Homo_sapiens

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