C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin alpha 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015533 Itga2 10090 - 13:114835916-114932041 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056117 Itga2-201 114835916-114932041 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056117
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056117 0.538±0.37 0.183±0.08 1.407±0.00 0.312±0.26 0.371±0.17 1.286±0.29 0.117±0.04 0.163±0.03 0.063±0.09 1.810±0.00 0.061±0.03 1.314±0.30 2.234±0.00 0.155±0.15

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0002687 IEA positive regulation of leukocyte migration
GO:0005178 IEA integrin binding
GO:0005515 IEA protein binding
GO:0005518 IEA collagen binding
GO:0005634 IEA nucleus
GO:0005886 TAS plasma membrane
GO:0005925 IEA focal adhesion
GO:0006928 IEA cellular component movement
GO:0006929 IEA substrate-dependent cell migration
GO:0006971 IEA hypotonic response
GO:0007155 IEA cell adhesion
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008283 IEA cell proliferation
GO:0008305 IEA integrin complex
GO:0009279 IEA cell outer membrane
GO:0009612 IEA response to mechanical stimulus
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010634 IEA positive regulation of epithelial cell migration
GO:0010694 IEA positive regulation of alkaline phosphatase activity
GO:0014070 IEA response to organic cyclic compound
GO:0014075 IEA response to amine
GO:0014850 IEA response to muscle activity
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0030424 IEA axon
GO:0030879 IEA mammary gland development
GO:0031346 IEA positive regulation of cell projection organization
GO:0031589 IEA cell-substrate adhesion
GO:0032403 IEA protein complex binding
GO:0032870 IEA cellular response to hormone stimulus
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0033343 IEA positive regulation of collagen binding
GO:0033591 IEA response to L-ascorbic acid
GO:0033627 IEA cell adhesion mediated by integrin
GO:0034666 IEA integrin alpha2-beta1 complex
GO:0038064 IEA collagen receptor activity
GO:0038065 IEA collagen-activated signaling pathway
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043236 IEA laminin binding
GO:0043388 IEA positive regulation of DNA binding
GO:0043589 IEA skin morphogenesis
GO:0043679 IEA axon terminus
GO:0045178 IDA basal part of cell
GO:0045184 IEA establishment of protein localization
GO:0045727 IEA positive regulation of translation
GO:0045785 IEA positive regulation of cell adhesion
GO:0045987 IEA positive regulation of smooth muscle contraction
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048333 IEA mesodermal cell differentiation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0050729 IEA positive regulation of inflammatory response
GO:0050927 IEA positive regulation of positive chemotaxis
GO:0050966 IEA detection of mechanical stimulus involved in sensory perception of pain
GO:0051971 IEA positive regulation of transmission of nerve impulse
GO:0060100 IEA positive regulation of phagocytosis, engulfment
GO:0070365 IEA hepatocyte differentiation
GO:0098639 IEA collagen binding involved in cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062974 itga2.2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), duplicate 2 protein_coding Danio_rerio
ENSDARG00000086838 ITGA2 (2 of 2) integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) protein_coding Danio_rerio
ENSG00000164171 ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) protein_coding Homo_sapiens

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