C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015656 Hspa8 10090 + 9:40800984-40805200 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015800 Hspa8-001 40800984-40805200 protein_coding
  ENSMUST00000117557 Hspa8-003 40801302-40805200 protein_coding
  ENSMUST00000117870 Hspa8-009 40801235-40805200 protein_coding
  ENSMUST00000127699 Hspa8-008 40802342-40802912 retained_intron
  ENSMUST00000133964 Hspa8-005 40801461-40802561 protein_coding
  ENSMUST00000138895 Hspa8-004 40801289-40802498 retained_intron
  ENSMUST00000140984 Hspa8-007 40801287-40803379 retained_intron
  ENSMUST00000149936 Hspa8-002 40801276-40805199 retained_intron
  ENSMUST00000153847 Hspa8-006 40801279-40804337 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015800ENSMUST00000117557ENSMUST00000117870ENSMUST00000153847
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015800 126.257±23.77 N/A 326.438±48.46 437.264±18.29 75.129±22.23 56.577±8.79 122.227±40.03 189.573±30.82 292.862±236.39 58.293±5.65 202.608±16.56 117.318±71.48 508.270±206.33 19.341±0.63
ENSMUST00000117557 N/A N/A N/A 177.255±0.00 N/A N/A N/A N/A N/A N/A N/A 186.375±69.85 422.742±359.76 21.456±0.00
ENSMUST00000117870 508.049±232.74 1436.772±364.64 N/A N/A 504.735±44.66 923.905±32.17 361.826±23.34 874.862±42.29 915.732±217.71 401.754±100.26 N/A 993.817±425.46 673.869±0.00 84.289±17.36
ENSMUST00000153847 534.432±124.58 564.243±70.64 N/A 438.402±14.12 531.644±195.84 376.348±40.99 420.611±21.32 706.194±54.85 329.256±36.18 311.657±47.45 N/A 553.465±130.04 587.244±282.90 70.542±3.32

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 IEA ubiquitin ligase complex
GO:0000974 ISS Prp19 complex
GO:0001664 IEA G-protein coupled receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005622 IDA intracellular
GO:0005634 ISS nucleus
GO:0005681 IEA spliceosomal complex
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0005925 IEA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0006397 IEA mRNA processing
GO:0006457 IDA protein folding
GO:0006950 IEA response to stress
GO:0008380 IEA RNA splicing
GO:0016020 IEA membrane
GO:0016887 IEA ATPase activity
GO:0019899 IEA enzyme binding
GO:0023026 IEA MHC class II protein complex binding
GO:0030529 ISS ribonucleoprotein complex
GO:0031072 IEA heat shock protein binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0042026 IEA protein refolding
GO:0042623 IDA ATPase activity, coupled
GO:0044822 IEA poly(A) RNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0048026 IMP positive regulation of mRNA splicing, via spliceosome
GO:0051082 IPI unfolded protein binding
GO:0051085 IGI chaperone mediated protein folding requiring cofactor
GO:0051726 IDA regulation of cell cycle
GO:0070062 IDA extracellular vesicular exosome
GO:0072318 IGI clathrin coat disassembly
GO:0072562 IEA blood microparticle
GO:1902904 IEA negative regulation of fibril organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037403 HSPA8 (1 of 2) heat shock 70kDa protein 8 protein_coding Danio_rerio
ENSDARG00000068992 hspa8 heat shock protein 8 protein_coding Danio_rerio
ENSG00000109971 HSPA8 heat shock 70kDa protein 8 protein_coding Homo_sapiens

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