C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxysteroid 11-beta dehydrogenase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000016194 Hsd11b1 10090 - 1:193221630-193264054 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000016338 Hsd11b1-002 193221636-193242591 protein_coding
  ENSMUST00000159644 Hsd11b1-004 193223647-193243524 protein_coding
  ENSMUST00000160929 Hsd11b1-003 193221836-193241597 protein_coding
  ENSMUST00000161406 Hsd11b1-006 193229454-193240410 protein_coding
  ENSMUST00000161737 Hsd11b1-001 193221630-193264054 protein_coding
  ENSMUST00000162842 Hsd11b1-005 193238070-193241424 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000016338ENSMUST00000159644ENSMUST00000160929ENSMUST00000161406ENSMUST00000161737
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000016338 4.556±2.51 N/A 10.415±0.00 0.965±0.90 7.295±2.43 0.531±0.19 0.873±0.28 N/A 43.896±35.16 N/A 1.555±0.56 0.543±0.27 9.259±12.06 0.128±0.05
ENSMUST00000159644 12.753±0.00 26.334±11.15 N/A 2.826±2.76 30.393±8.04 2.592±1.30 N/A 15.664±3.66 114.548±52.51 62.172±4.10 N/A 4.289±1.62 15.891±14.67 0.333±0.02
ENSMUST00000160929 26.274±15.45 23.133±5.70 12.626±0.88 3.197±0.00 47.328±10.97 2.869±0.75 5.911±2.26 38.004±3.49 203.317±189.17 102.116±8.70 1.826±0.00 2.629±2.30 12.463±11.54 0.322±0.27
ENSMUST00000161406 N/A N/A N/A 0.079±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000161737 N/A N/A 10.599±0.13 0.048±0.00 N/A 0.461±0.00 1.346±0.41 15.346±2.35 4.728±7.61 36.030±10.10 2.014±0.74 1.931±1.36 15.536±19.46 0.166±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZL CIL_0007ZL_0002 VISTA 1:192841048-193441723
CIL_00089N CIL_00089N_0002 VISTA 1:193149329-193750185

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003845 IMP 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
GO:0005783 IEA endoplasmic reticulum
GO:0008202 IEA steroid metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030324 IMP lung development
GO:0055114 IEA oxidation-reduction process
GO:0070524 IEA 11-beta-hydroxysteroid dehydrogenase (NADP+) activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069043 HSD11B1L (1 of 2) hydroxysteroid (11-beta) dehydrogenase 1-like protein_coding Danio_rerio
ENSDARG00000071377 hsd11b1la hydroxysteroid (11-beta) dehydrogenase 1-like a protein_coding Danio_rerio
ENSG00000117594 HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 protein_coding Homo_sapiens

Loading