C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nemo like kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017376 Nlk 10090 - 11:78567168-78697373 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000142739 Nlk-001 78567168-78697373 protein_coding
  ENSMUST00000165271 Nlk-002 78617272-78696494 retained_intron
  ENSMUST00000165475 Nlk-004 78567402-78568916 processed_transcript
  ENSMUST00000170394 Nlk-003 78567414-78572399 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000142739ENSMUST00000165271ENSMUST00000165475
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000142739 3.650±1.80 21.527±2.52 6.793±0.90 12.989±3.93 4.495±2.87 2.713±1.27 2.301±0.39 4.085±1.41 2.442±0.83 7.163±1.29 2.103±0.42 7.572±4.05 5.767±3.47 2.952±1.52
ENSMUST00000165271 N/A 13.240±3.59 N/A N/A 9.538±2.25 7.511±3.29 N/A 4.508±0.00 1.564±0.48 7.650±1.89 N/A 19.046±7.56 N/A N/A
ENSMUST00000165475 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.869±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000287 IDA magnesium ion binding
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004707 IDA MAP kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0007179 ISS transforming growth factor beta receptor signaling pathway
GO:0008134 ISS transcription factor binding
GO:0016055 IEA Wnt signaling pathway
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0031625 ISS ubiquitin protein ligase binding
GO:0033136 IDA serine phosphorylation of STAT3 protein
GO:0035556 IDA intracellular signal transduction
GO:0042169 IPI SH2 domain binding
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028793 nlk2 nemo like kinase, type 2 protein_coding Danio_rerio
ENSG00000087095 NLK nemo-like kinase protein_coding Homo_sapiens

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